Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/334158
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Sewage Protein Information Mining: Discovery of Large Biomolecules as Biomarkers of Population and Industrial Activities |
Autor: | Carrascal, Montserrat CSIC ORCID; Sánchez-Jiménez, Ester CSIC; Fang, Jie; Pérez-López, Carlos CSIC ORCID; Ginebreda Martí, Antoni CSIC ORCID; Barceló, Damià CSIC ORCID; Abián, Joaquín CSIC ORCID | Palabras clave: | Water fingerprinting Environmental proteomics Mass spectrometry Sewage epidemiology |
Fecha de publicación: | 1-ago-2023 | Editor: | American Chemical Society | Citación: | Environmental Science and Technology 57 (30): 10929–10939 (2023) | Resumen: | Wastewater-based epidemiology has been revealed as a powerful approach for surveying the health and lifestyle of a population. In this context, proteins have been proposed as potential biomarkers that complement the information provided by currently available methods. However, little is known about the range of molecular species and dynamics of proteins in wastewater and the information hidden in these protein profiles is still to be uncovered. In this study, we investigated the protein composition of wastewater from 10 municipalities in Catalonia with diverse populations and industrial activities at three different times of the year. The soluble fraction of this material was analyzed using liquid chromatography high-resolution tandem mass spectrometry using a shotgun proteomics approach. The complete proteomic profile, distribution among different organisms, and semiquantitative analysis of the main constituents are described. Excreta (urine and feces) from humans, and blood and other residues from livestock were identified as the two main protein sources. Our findings provide new insights into the characterization of wastewater proteomics that allow for the proposal of specific bioindicators for wastewater-based environmental monitoring. This includes human and animal population monitoring, most notably for rodent pest control (immunoglobulins (Igs) and amylases) and livestock processing industry monitoring (albumins). | Versión del editor: | https://doi.org/10.1021/acs.est.3c00535 | URI: | http://hdl.handle.net/10261/334158 | DOI: | 10.1021/acs.est.3c00535 | ISSN: | 0013936X |
Aparece en las colecciones: | (IDAEA) Artículos (IIBB) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
acs.est.3c00535.pdf | Artículo principal | 4,88 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
1
checked on 20-abr-2024
SCOPUSTM
Citations
2
checked on 23-abr-2024
WEB OF SCIENCETM
Citations
1
checked on 25-feb-2024
Page view(s)
28
checked on 26-abr-2024
Download(s)
41
checked on 26-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
Artículos relacionados:
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.