Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/307683
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | EphA7 receptor is expressed differentially at chicken prosomeric boundaries |
Autor: | García Calero, Elena CSIC; Puelles, Eduardo CSIC ORCID; Puelles, Luis | Fecha de publicación: | 2006 | Editor: | Elsevier | Citación: | Neuroscience 141(4): 1887-1897 (2006) | Resumen: | We reexamined tyrosine-kinase receptor EphA7 RNA signal in embryonic chicken forebrain, to clarify its topographic relationships with early regionalization processes, such as establishment of prosomeric boundaries. After neurulation, uniform alar expression appears across prospective prosomeres prosomere 1, prosomere 2 and prosomere 3 (prethalamus, thalamus and pretectum). This pattern soon changes by differential downregulation at or in between some of the prosomeric boundaries in an individual pattern for each limit, and by expansion of expression into the rostral midbrain. The secondary distribution highlights various transversal and longitudinal domains, notably the zona limitans intrathalamica and the pretectum limits, as well as two longitudinal bands in the basal plate, termed paramedian and parabasal. Strong expression of EphA7 appears at the mammillary pouch and a supramammillary tegmental arch from stage Hamburger and Hamilton stages 14–15 onwards. At the end of the developmental period examined, expression of EphA7 in the ventricular zone decreases generally (with some exceptions) and novel expression domains start to appear in the mantle layer, initiating a third phase of differential expression. Thus, while the expression of EphA7 does not show a fixed functional or topographic relationship to prosomeric boundaries, sequential transcription changes during chicken development are consistent with a differential involvement of the diverse interprosomeric boundaries, as well as dorsoventral patterning organizers, in the regulation of EphA7 expression. | Versión del editor: | https://doi.org/10.1016/j.neuroscience.2006.04.074 | URI: | http://hdl.handle.net/10261/307683 | DOI: | 10.1016/j.neuroscience.2006.04.074 | ISSN: | 0306-4522 |
Aparece en las colecciones: | (IN) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | 59,24 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
3
checked on 22-abr-2024
SCOPUSTM
Citations
12
checked on 01-may-2024
WEB OF SCIENCETM
Citations
11
checked on 25-feb-2024
Page view(s)
19
checked on 05-may-2024
Download(s)
3
checked on 05-may-2024
Google ScholarTM
Check
Altmetric
Altmetric
Artículos relacionados:
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.