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dc.contributor.author | Vázquez, Roberto | es_ES |
dc.contributor.author | Díez-Martínez, Roberto | es_ES |
dc.contributor.author | Domingo-Calap, Pilar | es_ES |
dc.contributor.author | García, Pedro | es_ES |
dc.contributor.author | Gutiérrez, Diana | es_ES |
dc.contributor.author | Muniesa, Maite | es_ES |
dc.contributor.author | Ruiz-Ruigómez, María | es_ES |
dc.contributor.author | Sanjuán, Rafael | es_ES |
dc.contributor.author | Tomás, María | es_ES |
dc.contributor.author | Tormo-Mas, María Ángeles | es_ES |
dc.contributor.author | García, Pilar | es_ES |
dc.date.accessioned | 2022-12-29T11:20:09Z | - |
dc.date.available | 2022-12-29T11:20:09Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Microorganisms 10(4): 717 (2022) | es_ES |
dc.identifier.uri | http://hdl.handle.net/10261/285825 | - |
dc.description | This article belongs to the Special Issue Bacteriophages-Based Technologies for a One Health Society: Applications in Clinical, Veterinary, and Industrial Settings. | es_ES |
dc.description.abstract | Antibiotic resistance is one of the major challenges that humankind shall face in the short term. (Bacterio)phage therapy is a valuable therapeutic alternative to antibiotics and, although the concept is almost as old as the discovery of phages, its wide application was hindered in the West by the discovery and development of antibiotics in the mid-twentieth century. However, research on phage therapy is currently experiencing a renaissance due to the antimicrobial resistance problem. Some countries are already adopting new ad hoc regulations to favor the short-term implantation of phage therapy in clinical practice. In this regard, the Phage Therapy Work Group from FAGOMA (Spanish Network of Bacteriophages and Transducing Elements) recently contacted the Spanish Drugs and Medical Devices Agency (AEMPS) to promote the regulation of phage therapy in Spain. As a result, FAGOMA was asked to provide a general view on key issues regarding phage therapy legislation. This review comes as the culmination of the FAGOMA initiative and aims at appropriately informing the regulatory debate on phage therapy. | es_ES |
dc.description.sponsorship | This work was supported by Grant RED2018-102589-T funded by MCIN/AEI/10.13039/501100011033. R.V. and D.G. were supported by the Research Foundation–Flanders (FWO) under grant [G066919N]. Pe. G. and R.V. were supported by the Spanish Ministry of Science and Innovation (Grant number SAF2017-88664-R), with additional funding provided by the Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), an initiative of the Instituto de Salud Carlos III. P.D.-C. was financially supported by a Ramón y Cajal contract RYC2019-028015-I and project PID2020-112835RA-I00 funded by MCIN/AEI/10.13039/501100011033, ESF Invest in your future, project SEJIGENT/2021/014, funded by Conselleria d’Innovació, Universitats, Ciència i Societat Digital (Generalitat Valenciana), and project AP2020-27 funded by VLC-Biomed (UV-La Fe 2020 Programa Acciones Preparatorias). M.M. was supported by project PID2020-113355GB-I00 of Spanish Ministry of Science and Innovation /Agencia Estatal de Investigación (AEI)/European regional fund (ERF). M.Á.T.-M. was supported by Spanish Ministry of Science and Innovation (Grant number SAF2017- 82251-R). | es_ES |
dc.format | application/pdf | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Multidisciplinary Digital Publishing Institute | es_ES |
dc.relation | info:eu-repo/grantAgreement/AEI//RED2018-102589-T | es_ES |
dc.relation | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2017-88664-R/ES/ENZIBIOTICOS CONTRA BACTERIAS PATOGENAS RESPIRATORIAS FORMADORAS DE BIOFILM/ | es_ES |
dc.relation | info:eu-repo/grantAgreement/AEI//RYC2019-028015-I | es_ES |
dc.relation | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-112835RA-I00/ES/HACIA UNA TERAPIA DE FAGOS CONTRA KLEBSIELLA PNEUMONIAE RESISTENTE A CARBAPENEMS/ | es_ES |
dc.relation | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-113355GB-I00/ES/EXPLORANDO EL POTENCIAL DEL INDICADOR DE CONTAMINACION FECAL HUMANA CRASSPHAGE EN ALIMENTOS Y AGUAS CONTAMINADAS FECALMENTE/ | es_ES |
dc.relation | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2017-82251-R/ES/NUEVAS ESTRATEGIAS DE PREVENCION Y DIAGNOSTICO DE LAS INFECCIONES RELACIONADAS CON DISPOSITIVOS BIOMEDICOS CAUSADOS POR STAPHYLOCOCCUS SPP/ | es_ES |
dc.relation.isversionof | Publisher's version | es_ES |
dc.rights | openAccess | es_ES |
dc.subject | Phage therapy | es_ES |
dc.subject | Drug regulation | es_ES |
dc.subject | Bacteriophages | es_ES |
dc.subject | Compassionate use | es_ES |
dc.subject | Endolysins | es_ES |
dc.subject | Antimicrobial resistance | es_ES |
dc.title | Essential topics for the regulatory consideration of phages as clinically valuable therapeutic agents: A perspective from Spain | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.3390/microorganisms10040717 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | https://doi.org/10.3390/microorganisms10040717 | es_ES |
dc.identifier.e-issn | 2076-2607 | - |
dc.rights.license | https://creativecommons.org/licenses/by/4.0/ | es_ES |
dc.contributor.funder | Ministerio de Ciencia, Innovación y Universidades (España) | es_ES |
dc.contributor.funder | Agencia Estatal de Investigación (España) | es_ES |
dc.contributor.funder | Research Foundation - Flanders | es_ES |
dc.contributor.funder | Instituto de Salud Carlos III | es_ES |
dc.contributor.funder | Generalitat Valenciana | es_ES |
dc.contributor.funder | European Commission | es_ES |
dc.relation.csic | Sí | es_ES |
oprm.item.hasRevision | no ko 0 false | * |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003359 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100004587 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003130 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100011033 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000780 | es_ES |
dc.identifier.pmid | 35456768 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.grantfulltext | open | - |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | artículo | - |
Aparece en las colecciones: | (I2SysBio) Artículos (CIB) Artículos |
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