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Título: | Mountain spa rehabilitation improved health of patients with post-COVID-19 syndrome: pilot study |
Autor: | Gvozdjáková, Anna; Sumbalova, Zuzana; Kucharská, Jarmila; Rausová, Zuzana; Kovalčíková, Eleonóra; Takácsová, Timea; Navas, Plácido CSIC ORCID; López-Lluch, Guillermo CSIC ORCID CVN ; Mojto, Viliam; Palacka, Patrik | Palabras clave: | High-altitude environment Mountain spa rehabilitation Post-COVID-19 syndrome SARS-CoV-2 Pulmonary function Clinical symptoms Platelet mitochondrial metabolism Coenzyme Q10 Oxidative stress |
Fecha de publicación: | 23-sep-2022 | Editor: | Springer Nature | Citación: | Environmental Science and Pollution Research (2022) | Resumen: | European Association of Spa Rehabilitation (ESPA) recommends spa rehabilitation for patients with post-COVID-19 syndrome. We tested the hypothesis that a high-altitude environment with clean air and targeted spa rehabilitation (MR — mountain spa rehabilitation) can contribute to the improving platelet mitochondrial bioenergetics, to accelerating patient health and to the reducing socioeconomic problems. Fifteen healthy volunteers and fourteen patients with post-COVID-19 syndrome were included in the study. All parameters were determined before MR (MR1) and 16–18 days after MR (MR2). Platelet mitochondrial respiration and OXPHOS were evaluated using high resolution respirometry method, coenzyme Q10 level was determined by HPLC, and concentration of thiobarbituric acid reactive substances (TBARS) as a parameter of lipid peroxidation was determined spectrophotometrically. This pilot study showed significant improvement of clinical symptoms, lungs function, and regeneration of reduced CI-linked platelet mitochondrial respiration after MR in patients with post-COVID-19 syndrome. High-altitude environment with spa rehabilitation can be recommended for the acceleration of recovery of patients with post-COVID-19 syndrome. | Versión del editor: | https://doi.org/10.1007/s11356-022-22949-2 | URI: | http://hdl.handle.net/10261/281502 | DOI: | 10.1007/s11356-022-22949-2 | ISSN: | 0944-1344 | E-ISSN: | 1614-7499 |
Aparece en las colecciones: | (PTI Salud Global) Colección Especial COVID-19 (CABD) Artículos |
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s11356-022-22949-2.pdf | 1,11 MB | Adobe PDF | Visualizar/Abrir |
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