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http://hdl.handle.net/10261/251567
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Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Hernández, Félix | es_ES |
dc.contributor.author | Lim, Filip | es_ES |
dc.contributor.author | Lucas, José Javier | es_ES |
dc.contributor.author | Pérez Martín, María Concepción | es_ES |
dc.contributor.author | Moreno, Francisco J. | es_ES |
dc.contributor.author | Ávila, Jesús | es_ES |
dc.date.accessioned | 2021-10-05T06:55:17Z | - |
dc.date.available | 2021-10-05T06:55:17Z | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | Mini-Reviews in Medicinal Chemistry 2(1): 51-58 (2002) | es_ES |
dc.identifier.issn | 1389-5575 | - |
dc.identifier.uri | http://hdl.handle.net/10261/251567 | - |
dc.description | open access plus | es_ES |
dc.description.abstract | The deposit of two proteins in the brain characterizes Alzheimers disease: deposits of β-amyloid protein to form senile plaques and tau protein in neurofibrillary tangles. This review discusses transgenic animals overexpressing normal or mutated tau protein as well as kinases involved in tau hyperphosphorylation. These animals hold a great potential as tools to test the effects of forthcoming therapeutical agents for Alzheimers disease. | es_ES |
dc.description.sponsorship | This work has been supported in part by grants from Spanish CICYT and Comunidad de Madrid, Neuropharma and by an institutional grant from Fundación R. Areces. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Bentham Science Publishers | es_ES |
dc.relation.isversionof | Publisher's version | es_ES |
dc.rights | openAccess | es_ES |
dc.subject | Tau pathology | es_ES |
dc.subject | Tau hyperphosphorylation | es_ES |
dc.subject | Alzheimers disease | es_ES |
dc.title | Transgenic mouse models with tau pathology to test therapeutic agents for Alzheimer's disease | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.2174/1389557023406557 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | https://doi.org/10.2174/1389557023406557 | es_ES |
dc.contributor.funder | Comisión Interministerial de Ciencia y Tecnología, CICYT (España) | es_ES |
dc.contributor.funder | Comunidad de Madrid | es_ES |
dc.contributor.funder | Fundación Ramón Areces | es_ES |
dc.relation.csic | Sí | es_ES |
oprm.item.hasRevision | no ko 0 false | * |
dc.identifier.funder | http://dx.doi.org/10.13039/100012818 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100007273 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/100008054 | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | With Fulltext | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.openairetype | artículo | - |
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transgenidisea.pdf | 66,66 kB | Adobe PDF | Visualizar/Abrir |
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