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http://hdl.handle.net/10261/243098
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Título: | Method for predicting the response to treatment with radiotherapy combined with chemotherapy based on cisplatin |
Autor: | Ibáñez de Cáceres, Inmaculada CSIC ORCID; Belda-Iniesta, Cristobal; Pernía, Olga CSIC; Perona Abellón, Rosario CSIC ORCID; Cortés-Sempere, María CSIC | Fecha de publicación: | 5-may-2016 | Citación: | US2016/0122828 A1 | Resumen: | The invention relates to a method to predict the response to treatment with radiotherapy combined with cisplatin-based chemotherapy in patients with cancer, preferably non-microcytic lung cancer, wherein said method is based on the detection of the presence of methylation in the IGFBP-3 gene. The present invention also relates to an in vitro method to design a customised treatment for an individual with said disease. The method of the invention may be quantitative or semi-quantitative. The present invention also relates to a probe designed for the quantitative detection of the methylation of the IGFBP-3 gene, to a kit that comprises it and to the use of the kit to predict the response of a subject to the aforementioned treatment | URI: | http://hdl.handle.net/10261/243098 |
Aparece en las colecciones: | (IIBM) Patentes |
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US2016122828A1.pdf | 8,81 MB | Adobe PDF | Visualizar/Abrir |
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