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Título

Method for predicting the response to treatment with radiotherapy combined with chemotherapy based on cisplatin

AutorIbáñez de Cáceres, Inmaculada CSIC ORCID; Belda-Iniesta, Cristobal; Pernía, Olga CSIC; Perona Abellón, Rosario CSIC ORCID; Cortés-Sempere, María CSIC
Fecha de publicación5-may-2016
CitaciónUS2016/0122828 A1
ResumenThe invention relates to a method to predict the response to treatment with radiotherapy combined with cisplatin-based chemotherapy in patients with cancer, preferably non-microcytic lung cancer, wherein said method is based on the detection of the presence of methylation in the IGFBP-3 gene. The present invention also relates to an in vitro method to design a customised treatment for an individual with said disease. The method of the invention may be quantitative or semi-quantitative. The present invention also relates to a probe designed for the quantitative detection of the methylation of the IGFBP-3 gene, to a kit that comprises it and to the use of the kit to predict the response of a subject to the aforementioned treatment
URIhttp://hdl.handle.net/10261/243098
Aparece en las colecciones: (IIBM) Patentes




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