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Título: | 3DBionotes COVID-19 Edition |
Autor: | Macías, José Ramón; Sánchez-García, Rubén; Conesa Mingo, Pablo; Ramírez-Aportela, Erney CSIC ORCID; Martínez González, Mar; Wert-Carvajal, Carlos CSIC ORCID; Parra-Pérez, Alberto M.; Segura, Joan; Horrell, Sam; Thorn, Andrea; Sorzano, Carlos Óscar S.; Carazo, José M. | Fecha de publicación: | 20-may-2021 | Editor: | Oxford University Press | Citación: | Bioinformatics - Oxford btab397 (2021) | Resumen: | The web platform 3DBionotes-WS integrates multiple Web Services and an interactive Web Viewer to provide a unified environment in which biological annotations can be analyzed in their structural context. Since the COVID-19 outbreak, new structural data from many viral proteins have been provided at a very fast pace. This effort includes many cryogenic Electron Microscopy (cryo-EM) studies, together with more traditional ones (X-rays, NMR), using several modeling approaches and complemented with structural predictions. At the same time, a plethora of new genomics and interactomics information (including fragment screening and structure-based virtual screening efforts) have been made available from different servers. In this context we have developed 3DBionotes-COVID-19 as an answer to: (1) The need to explore multi-omics data in a unified context with a special focus on structural information and (2) the drive to incorporate quality measurements, especially in the form of advanced validation metrics for cryogenic Electron Microscopy. | Descripción: | https://3dbionotes.cnb.csic.es/ws/covid19 | Versión del editor: | https://doi.org/10.1093/bioinformatics/btab397 | URI: | http://hdl.handle.net/10261/241575 | DOI: | 10.1093/bioinformatics/btab397 | ISSN: | 1367-4803 | E-ISSN: | 1460-2059 |
Aparece en las colecciones: | (PTI Salud Global) Colección Especial COVID-19 (CNB) Artículos |
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btab397.pdf | 323,87 kB | Adobe PDF | Visualizar/Abrir |
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