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http://hdl.handle.net/10261/221216
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Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Rincón, Ana María | es_ES |
dc.contributor.author | Monje-Casas, Fernando | es_ES |
dc.date.accessioned | 2020-10-15T07:59:23Z | - |
dc.date.available | 2020-10-15T07:59:23Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Cell Cycle 19(12): 1405-1421 (2020) | es_ES |
dc.identifier.issn | 1538-4101 | - |
dc.identifier.uri | http://hdl.handle.net/10261/221216 | - |
dc.description.abstract | The spindle constitutes the cellular machinery that enables the segregation of the chromosomes during eukaryotic cell division. The microtubules that form this fascinating and complex genome distribution system emanate from specialized structures located at both its poles and known as microtubule-organizing centers (MTOCs). Beyond their structural function, the spindle MTOCs play fundamental roles in cell cycle control, the activation and functionality of the mitotic checkpoints and during cellular aging. This review highlights the pivotal importance of spindle-associated MTOCs in multiple cellular processes and their central role as key regulatory hubs where diverse intracellular signals are integrated and coordinated to ensure the successful completion of cell division and the maintenance of the replicative lifespan. | es_ES |
dc.description.sponsorship | Research in the Monje-Casas' laboratory was supported by the European Union (FEDER) and the Spanish Ministry of Science, Innovation and Universities [BFU2017-92284-EXP]; European Union (FEDER) and the Spanish Ministry of Science, Innovation and Universities [BFU2016-76642-P]. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Taylor & Francis | es_ES |
dc.relation | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/BFU2017-92284-EXP | es_ES |
dc.relation | BFU2017-92284-EXP/AEI/10.13039/501100011033 | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BFU2016-76642-P | es_ES |
dc.rights | closedAccess | es_ES |
dc.subject | Centrosomes | es_ES |
dc.subject | Mitosis | es_ES |
dc.subject | Meiosis | es_ES |
dc.subject | Aging | es_ES |
dc.title | A guiding torch at the poles: the multiple roles of spindle microtubule-organizing centers during cell division | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1080/15384101.2020.1754586 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | https://doi.org/10.1080/15384101.2020.1754586 | es_ES |
dc.identifier.e-issn | 1551-4005 | - |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | es_ES |
dc.contributor.funder | Agencia Estatal de Investigación (España) | es_ES |
dc.contributor.funder | Ministerio de Ciencia, Innovación y Universidades (España) | es_ES |
dc.contributor.funder | European Commission | es_ES |
dc.relation.csic | Sí | es_ES |
oprm.item.hasRevision | no ko 0 false | * |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003329 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000780 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100011033 | es_ES |
dc.contributor.orcid | Rincón, Ana María [0000-0002-7044-5553] | es_ES |
dc.contributor.orcid | Monje-Casas, Fernando [0000-0002-3587-2373] | es_ES |
dc.identifier.pmid | 32401610 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
item.openairetype | artículo | - |
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