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Título: | A perspective on microneedle-based drug delivery and diagnostics in paediatrics |
Autor: | Pires, Liliana R.; Vinayakumar, K.B.; Turos, María; Miguel, Verónica CSIC ORCID; Gaspar, Joao | Palabras clave: | Microneedles Medical devices Paediatrics |
Fecha de publicación: | 15-nov-2019 | Citación: | Journal of Personalized Medicine 9: 49 (2019) | Resumen: | Microneedles (MNs) have been extensively explored in the literature as a means to deliver drugs in the skin, surpassing the stratum corneum permeability barrier. MNs are potentially easy to produce and may allow the self-administration of drugs without causing pain or bleeding. More recently, MNs have been investigated to collect/assess the interstitial fluid in order to monitor or detect specific biomarkers. The integration of these two concepts in closed-loop devices holds the promise of automated and minimally invasive disease detection/monitoring and therapy. These assure low invasiveness and, importantly, open a window of opportunity for the application of population-specific and personalised therapies | Versión del editor: | http://dx.doi.org/10.3390/jpm9040049 | URI: | http://hdl.handle.net/10261/213197 | DOI: | 10.3390/jpm9040049 | Identificadores: | doi: 10.3390/jpm9040049 issn: 2075-4426 |
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MiguelV_PerspectiveonMicroneedle.pdf | 1,21 MB | Adobe PDF | Visualizar/Abrir |
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