Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/191952
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Bioconcentration of pesticides in Zebrafish eleutheroembryos (Danio rerio) |
Autor: | El-Amrani, S.; Pena-Abaurrea, Miren CSIC ORCID; Sanz-Landaluze, Jon; Ramos, Lourdes CSIC ORCID ; Guinea, J.; Cámara, C. | Palabras clave: | Bioconcentration factor Zebrafish eleutheroembryo Atrazine Dicofol |
Fecha de publicación: | 2012 | Editor: | Elsevier | Citación: | Science of the Total Environment 425: 184-190 (2012) | Resumen: | The feasibility of a bioaccumulation test based on the use of zebrafish eleutheroembryos as an alternative to adult-individual-based approaches for REACH application has been evaluated for three test compounds, chlorpyrifos, dicofol and atrazine. Following the OECD 305 guidelines, zebrafish eleutheroembryos (72 h after hatching, hpf) were separately exposed to the investigated pesticides at two nominal concentrations below 1% of its corresponding LC50. The uptake experiments lasted for 48 h. Then, the exposure medium was replaced by a non-contaminated medium for depuration experiments (up to 72 h). Zebrafish eleutheroembryos (larvae 144 hpf, i.e. at the end of the depuration step) and their corresponding exposure media was sampled at ten different times during each experiment and the concentration of the investigated pesticide determined in both the organisms and in the exposure medium. The experimentally determined pesticide accumulation profiles in the eleutheroembryos demonstrated that atrazine has a very fast accumulation kinetic, reaching steady sate (SS) within 24 h. Chlorpyrifos and dicofol did not reach the SS within the 48-h uptake experiments although they exhibit higher accumulations than the former pesticide. Two toxicokinetic models were used to calculate the bioconcentration factor (BCF) of the studied pesticide in zebrafish eleutheroembryos. In the former, the BCF was calculated under SS conditions (BCFSS). The second was used when the compounds did not reach the SS during the uptake experiment (BCFk). Log BCF values of 3.55 and 3.84 for chlorpyrifos; 0.6 and 1.17 for atrazine, and 3.90 for dicofol were experimentally calculated at selected exposure concentrations. These values have been compared with those reported in related bioaccumulation studies and official databases. | Versión del editor: | https://doi.org/10.1016/j.scitotenv.2012.02.065 | URI: | http://hdl.handle.net/10261/191952 | DOI: | 10.1016/j.scitotenv.2012.02.065 | ISSN: | 0048-9697 | E-ISSN: | 1879-1026 |
Aparece en las colecciones: | (IQOG) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | 59,24 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
7
checked on 05-may-2024
SCOPUSTM
Citations
68
checked on 06-may-2024
WEB OF SCIENCETM
Citations
66
checked on 25-feb-2024
Page view(s)
239
checked on 13-may-2024
Download(s)
31
checked on 13-may-2024
Google ScholarTM
Check
Altmetric
Altmetric
Artículos relacionados:
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.