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| Título: | Covalent immobilisation of magnetic nanoparticles on surfaces via strain-promoted azide–alkyne click chemistry |
Autor: | Fratila, Raluca M. CSIC ORCID; Navascuez, Marcos; Idiago López, Francisco Javier CSIC ORCID; Eceiza, Maite; Miranda, José Ignacio; Aizpurua, Jesús M.; Fuente, Jesús M. de la CSIC ORCID | Fecha de publicación: | 2017 | Editor: | Royal Society of Chemistry (UK) | Citación: | New Journal of Chemistry 41(19): 10835-10840 (2017) | Resumen: | Herein we report the synthesis of “clickable” magnetic nanoparticles (MNPs) stable in suspension in physiological media for bioorthogonal click chemistry applications. These MNPs incorporate into their coating a cyclooctynyl derivative for strain-promoted azide–alkyne (SPAAC) cycloaddition and either a polyethylene glycol or a glucose moiety to ensure MNP stability in physiological media. Their reactivity towards azide-functionalised Si surfaces was investigated, demonstrating their potential as bioorthogonal probes. | Versión del editor: | https://doi.org/10.1039/C7NJ01822C | URI: | http://hdl.handle.net/10261/181851 | DOI: | 10.1039/C7NJ01822C | ISSN: | 1144-0546 | E-ISSN: | 1369-9261 |
| Aparece en las colecciones: | (ICMA) Artículos |
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| covalentchemistry.pdf | 3,1 MB | Adobe PDF |  Visualizar/Abrir |
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