1. DIGITAL.CSIC

Elena, Santiago F.

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Perfil

SFElena.1.jpg picture
 
Firma en Digital.CSIC (*)
Elena, Santiago F.
 
Otras firmas
Elena Fito, Santiago F.
 
Centro o Instituto
CSIC - UV Instituto de Biología Integrativa de Sistemas (I2SysBio)
 
Departamento
Biología de Sistemas de Patógenos
 
Categoría Profesional
Profesor de Investigación
 
Especialización
In general, my scientific interests are related with the evolutionary biology of microbes. More concretely, this interest is focused in the study, within the framework of Populations Genetics, of the mechanisms that generate and maintain the genetic variability of RNA viruses. The model systems that we use now for our experiments are the RNA viruses Tobacco etch potyvirus (TEV) and Turnip mosaic potyvirus (TuMV), the para-retrovirus Cauliflower mosaic caulimovirus (CaMV), and the viroids. I have also been exploring the endless potential of digital organisms as model systems for evolutionary studies. And finally, to avoid missing the wave of Systems Biology we are now developing in silico and mathematical hierarchical models of the entire viral infectious cycle.
 
Email
santiago.elena@csic.es
 
ORCID
 
Página web
 
Otros identificadores (con url)
 

Publications

Resultados 41-60 de 164.

DerechosPreviewFecha Public.TítuloAutor(es)Tipo
41openAccess2023Effect of disease prevalence and growth stage on symptom severity in the Turnip mosaic virus – Arabidopsis thaliana pathosystemIglesia, Francisca de la CSIC; Elena, Santiago F. CSIC ORCID artículo
42openAccessEffect_genetic_robustness.pdf.jpg14-oct-2008The effect of genetic robustness on evolvability in digital organismsElena, Santiago F. CSIC ORCID ; Sanjuán, Rafael CSIC ORCIDartículo
43openAccessPLOS GENETICS 7_e1002378.pdf.jpg17-nov-2011Effect of Host Species on the Distribution of Mutational Fitness Effects for an RNA VirusLalic, Jasna CSIC ORCID; Cuevas, José M. CSIC ORCID; Elena, Santiago F. CSIC ORCID artículo
44openAccessZwart et al. JVI.pdf.jpgsep-2012Effects of Potyvirus Effective Population Size in Inoculated Leaves on Viral Accumulation and the Onset of SymptomsZwart, Mark P. CSIC ORCID; Daròs Arnau, José Antonio CSIC ORCID ; Elena, Santiago F. CSIC ORCID artículo
45openAccessSanchez-NavarroetalJVirol.pdf.jpgoct-2013Effects of the number of genome segments on primary and systemic infection for a multipartite plant RNA virusElena, Santiago F. CSIC ORCID ; Sánchez-Navarro, J. A. ; Zwart, Mark P. CSIC ORCIDartículo
46openAccessPlosOne_8_e66700.pdf.jpg20-jun-2013Emergence and Phylodynamics of Citrus tristeza virus in Sicily, ItalyDavino, Salvatore; Willemsen, Anouk CSIC ORCID; Panno, Stefano; Davino, Mario; Catara, Antonino; Elena, Santiago F. CSIC ORCID ; Rubio, Luisartículo
47openAccessBedhomme et al Curr Opin Virol.pdf.jpg1-nov-2014Emerging viruses: why they are not jacks of all trades?Bedhomme, Stéphanie CSIC ORCID; Hillung, Julia CSIC ORCID; Elena, Santiago F. CSIC ORCID artículo
48openAccessengingenome.pdf.jpg2018Engineered functional redundancy relaxes selective constraints upon endogenous genes in viral RNA genomesAmbrós, Silvia CSIC ORCID; Iglesia, Francisca de la CSIC; Rosario, Sttefany M.; Butkovic, Anamarija CSIC ORCID; Elena, Santiago F. CSIC ORCID artículo
49openAccess1475-4924-2-12.pdf.jpg3-jun-2003Environmental stress and the effects of mutationElena, Santiago F. CSIC ORCID ; Visser, J. Arjan G.M. deartículo
50openAccessLalic Elena Biol Lett.pdf.jpgfeb-2013Epistasis between mutations is host-dependent for an RNA virusLalic, Jasna CSIC ORCID; Elena, Santiago F. CSIC ORCID artículo
51closedAccess18-sep-2006Epistasis correlates to genomic complexitySanjuán, Rafael CSIC ORCID; Elena, Santiago F. CSIC ORCID artículo
52openAccesssardanyes_elena_jtb_R2_def.pdf.jpgjun-2010Error threshold in RNA quasispecies models with complementationSardanyés, Josep CSIC ORCID; Elena, Santiago F. CSIC ORCID artículo
53openAccessTromas et al 2014 J. Gen. Virol.pdf.jpg2014Estimation of the in vivo recombination rate for a plant RNA virusTromas, Nicolas; Zwart, Mark P. CSIC ORCID; Maïté, Poulain; Elena, Santiago F. CSIC ORCID artículo
54closedAccessaccesoRestringido.pdf.jpg2019Evolution and ecology of plant virusesLefeuvre, Pierre; Martin, Darren P.; Elena, Santiago F. CSIC ORCID ; Shepherd, Dionne N.; Roumagnac, Philippe; Varsani, Arvindartículo
55openAccessElena et al. Adv. Virus Res.pdf.jpg2014Evolution and emergence of plant virusesElena, Santiago F. CSIC ORCID ; Fraile, A.; García-Arenal, Fernandoartículo
56openAccessMushegian Elena Virology 2015.pdf.jpg9-ene-2015Evolution of plant virus movement proteins from the 30K superfamily and of their homologs integrated in plant genomesMushegian, Arcady R.; Elena, Santiago F. CSIC ORCID artículo
57closedAccessfeb-2007The evolution of sex: empirical insights into the roles of epistasis and driftVisser, J. de; Elena, Santiago F. CSIC ORCID ; Arjan, G. M.artículo
58openAccessElena et al-TOVJ09.pdf.jpg17-feb-2009The evolution of viruses in multi-host fitness landscapesElena, Santiago F. CSIC ORCID ; Agudelo-Romero, Patricia CSIC ORCID; Lalic, Jasna CSIC ORCIDartículo
59openAccessElena et al Viruses.pdf.jpg2009Evolutionary constraints to viroid evolutionElena, Santiago F. CSIC ORCID ; Gómez, Gustavo CSIC ORCID ; Daròs Arnau, José Antonio CSIC ORCID artículo
60openAccess2012Evolved Modular Epistasis in Artificial OrganismsValverde, Sergi CSIC ORCID ; Solé, Ricard V. CSIC ORCID ; Elena, Santiago F. CSIC ORCID artículo