Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
closedAccess | | 2017 | A natural product inhibits the initiation of α-synuclein aggregation & suppresses its toxicity | Perni, M.; Galvagnion, C.; Maltsev, A.; Meisl, G.; Müller, M.B.D.; Challa, P.K.; Kirkegaard, J.B.; Flagmeier, P.; Cohen, S.I.A.; Cascella, R.; Chen, S.W.; Limbocker, Ryan; Sormanni, P.; Heller, G.T.; Aprile, F.A.; Cremades, Nunilo; Cecchi, C.; Chiti, Fabrizio; Nollen, E.A.A.; Knowles, T.P.J.; Vendruscolo, M.; Bax, A.; Zasloff, M.; Dobson, C.M. | artículo |
closedAccess | | 2017 | Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein Species | Aprile, F.A.; Arosio, P.; Fusco, Giuliana; Chen, S.W.; Kumita, J.R.; Dhulesia, Anne; Tortora, P.; Knowles, T.P.J.; Vendruscolo, M.; Dobson, C.M.; Cremades, Nunilo | artículo |
openAccess | | 28-jun-2018 | Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine | Perni, Michele; Flagmeier, P.; Limbocker, Ryan; Cascella, R.; Aprile, Francesco A.; Galvagnion, C.; Heller, G.T.; Meisl, G.; Chen, S.W.; Kumita, J.R.; Challa, P.K.; Kirkegaard, J.B.; Cohen, S.I.A.; Mannini, Benedetta; Barbut, Denise; Nollen, E.A.A.; Cecchi, C.; Cremades, Nunilo; Knowles, Tuomas P. J.; Chiti, Fabrizio; Zasloff, Michael; Vendruscolo, Michele; Dobson, Christopher M. | artículo |
openAccess | | 15-oct-2020 | The extent of protein hydration dictates the preference for heterogeneous or homogeneous nucleation generating either parallel or antiparallel β-sheet α-synuclein aggregates | Camino, José D.; Gracia, Pablo; Chen, S.W.; Sot, Jesús CSIC ORCID; Arada, Igor de la CSIC ORCID; Sebastián, Víctor CSIC ORCID; Arrondo, José Luis R.; Goñi, Félix M. CSIC ORCID; Dobson, Christopher M.; Cremades, Nunilo | artículo |
openAccess | | 13-ago-2020 | Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism | Limbocker, Ryan; Mannini, Benedetta; Ruggeri, F.S.; Cascella, R.; Xu, C.K.; Perni, M.; Chia, S.; Chen, S.W.; Habchi, J.; Bigi, A.; Kreiser, R.P.; Wright, A.K.; Albright, J.A.; Kartanas, T.; Kumita, J.R.; Cremades, Nunilo; Zasloff, M.; Cecchi, C.; Knowles, T.P.J.; Chiti, Fabrizio; Vendruscolo, M.; Dobson, Christopher M. | artículo |