Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
closedAccess | | 2013 | A therapeutic approach to cerebrovascular diseases based on indole substituted hydrazides and hydrazines able to interact with human vascular adhesion protein-1, monoamine oxidases (A and B), AChE and BuChE | Esteban, Gerard; Bolea, Irene; Sun, Ping; Solé, Montserrat CSIC ORCID ; Samadi, Abdelouahid CSIC ORCID; Marco-Contelles, José CSIC ORCID; Unzeta, Mercedes | artículo |
openAccess | | 28-jun-2016 | ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy | Marco-Contelles, José CSIC ORCID; Unzeta, Mercedes; Bolea, Irene; Esteban, Gerard; Ramsay, Rona R.; Romero Jódar, Alejandro CSIC ORCID; Martínez-Murillo, Ricardo CSIC ORCID; Carreiras, M. Carmo; Ismaili, L. | artículo |
closedAccess | | 2014 | Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease | Bautista-Aguilera, Óscar M. CSIC ORCID; Esteban, Gerard; Bolea, Irene; Nikolic, Katarina; Agbaba, Danica; Moraleda, Ignacio; Iriepa, Isabel; Samadi, Abdelouahid CSIC ORCID; Soriano, Elena CSIC; Unzeta, Mercedes; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 2014 | Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease | Wang, L.; Esteban, Gerard; Ojima, Masaki; Bautista-Aguilera, Óscar M. CSIC ORCID; Inokuchi, Tsutomu; Moraleda, Ignacio; Iriepa, Isabel; Samadi, Abdelouahid CSIC ORCID; Youdim, Moussa B. H.; Romero Jódar, Alejandro CSIC ORCID; Soriano, Elena CSIC; Herrero-Labrador, Raquel CSIC ORCID; Fernández Fernández, Ana Patricia CSIC; Martínez-Murillo, Ricardo CSIC ORCID; Marco-Contelles, José CSIC ORCID; Unzeta, Mercedes | artículo |
closedAccess | | 2017 | In-vitro and in-vivo evaluation of the modulatory effects of the multitarget compound ASS234 on the monoaminergic system | Esteban, Gerard; Van Schoors, J.; Sun, P.; Van Eeckhaut, Ann; Marco-Contelles, José CSIC ORCID; Smolders, I.; Unzeta, M. | artículo |
closedAccess | | 2014 | Kinetic and structural analysis of the irreversible inhibition of human monoamine oxidases by ASS234, a multi-target compound designed for use in Alzheimer's disease | Esteban, Gerard; Allan, Jennifer; Samadi, Abdelouahid CSIC ORCID; Mattevi, Andrea; Unzeta, Mercedes; Marco-Contelles, José CSIC ORCID; Binda, Claudia; Ramsay, Rona R. | artículo |
openAccess | | 25-may-2016 | Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease | Unzeta, Mercedes; Esteban, Gerard; Bolea, Irene; Fogel, W. Agnieszka; Ramsay, Rona R.; Youdim, Moussa B. H.; Tipton, Keith Francis; Marco-Contelles, José CSIC ORCID | artículo |
openAccess | | 2014 | Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: Design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids | Bautista-Aguilera, Óscar M. CSIC ORCID; Esteban, Gerard; Chioua, Mourad CSIC ORCID ; Nikolic, Katarina; Agbaba, Danica; Moraleda, Ignacio; Iriepa, Isabel; Soriano, Elena CSIC; Samadi, Abdelouahid CSIC ORCID; Unzeta, Mercedes; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 1996 | Neuronal and Non-Neuronal Localization of Acid Sulfated Glycosaminoglycans (sGAG) and Chondroitin Proteoglycans in the Rat Medulla Oblongata | Gragera, R.R.; Muñiz, E.; Esteban, Gerard; Alonso, M. J.; López-Bravo, A. CSIC; González-Romero, F. J.; Martínez-Murillo, Ricardo CSIC ORCID; Toledano Gasca, Adolfo CSIC ORCID CVN; Martínez-Rodríguez, Ricardo | artículo |