Mostrando resultados 13 a 30 de 30
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Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
openAccess | | 13-jun-2003 | Leads for development of new naphthalenesulfonate derivatives with enhanced antiangiogenic activity: crystal structure of acidic fibroblast growth factor in complex with 5-amino-2-naphthalene sulfonate | Fernández-Tornero, Carlos CSIC ORCID ; Lozano, R.M. CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Gómez, Ana M. CSIC ORCID ; López, José C.; Quesada, Ernesto CSIC ORCID ; Uriel, Clara CSIC ORCID; Valverde, Serafín; Romero, Antonio CSIC ORCID ; Giménez-Gallego, Guillermo CSIC | artículo |
openAccess | | 3-jun-2017 | Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions. | Tang, Yong; Rodríguez-Salarichs, Javier CSIC; Estévez-Gallego, Juan CSIC ORCID ; Balaguer, Francisco de Asís CSIC ORCID; Redondo-Horcajo, Mariano CSIC ORCID ; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuo | artículo |
openAccess | | 21-sep-2001 | Solution structure and interaction with basic and acidic fibroblast growth factor of a 3-kDa human platelet factor-4 fragment with antiangiogenic activity | Lozano, R.M. CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Jiménez, M. Angeles CSIC ORCID ; Zilberberg, Lior; Cuevas, Pedro; Bikfalvi, Andreas; Rico, Manuel CSIC; Giménez-Gallego, Guillermo CSIC | artículo |
closedAccess | | 12-ago-2016 | Structural and Biochemical Characterization of the Interaction of Tubulin with Potent Natural Analogues of Podophyllotoxin | Antúnez-Mojica, Mayra; Rodríguez-Salarichs, Javier CSIC; Redondo-Horcajo, Mariano CSIC ORCID ; León, Alejandra; Barasoain, Isabel CSIC ; Canales, Ángeles CSIC ORCID; Cañada, F. Javier ; Jiménez-Barbero, Jesús CSIC ORCID; Álvarez, Laura CSIC ORCID; Díaz, José Fernando CSIC ORCID | artículo |
openAccess | | 16-feb-2017 | Structural basis of microtubule stabilization by discodermolide | Prota, Andrea E.; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Smith III, Amos B.; Yang, Chia-Ping H.; McDaid, Hayley M.; Paterson, Ian; Horwitz, Susan; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O. | artículo |
openAccess | | 13-dic-2016 | Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells | Trigili, Chiara CSIC; Barasoain, Isabel CSIC ; Sánchez-Murcia, Pedro A. CSIC ORCID; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Nogales, Aurora CSIC ORCID; Gardner, Nicola M.; Meyer, Arndt; Naylor, Guy J.; Gomez-Rubio, Elena CSIC ORCID; Gago, Federico CSIC ORCID; Steinmetz, Michel O.; Paterson, Ian; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID | artículo |
closedAccess | | sep-2016 | Synthesis and Anti-Proliferative Activity of Sulfanyltriazolylnaphthalenols and Sulfanyltriazolylnaphthalene-1,4-diones | Chaaban, Ibrahim; El Khawass, El Sayeda M.; Abd El Razik, Heba A.; El Salamouni, Nehad S.; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Yli-Kauhaluoma, Jari; Moreira, Vânia M. | artículo |
closedAccess | | 28-feb-2013 | Synthesis and biological evaluation as microtubule-active agents of several tetrahydrofuran and spiroacetal derivatives | Carda, Miguel; Murga, Juan; Paños, Julián; Angulo-Pachón, C.A.; García-Pla, Jorge; Díaz-Oltra, Santiago; Marco, J. Alberto; Trigili, Chiara CSIC; Redondo-Horcajo, Mariano CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC | artículo |
closedAccess | | 2012 | Synthesis and Biological Evaluation of Colchicine B‑Ring Analogues Tethered with Halogenated Benzyl Moieties | Cosentino, Laura; Redondo-Horcajo, Mariano CSIC ORCID ; Zhao, Ying; Santos, Ana Rita; Chowdury, Kaniz F.; Vinader, Victoria; Abdallah, Qasem M. A.; Abdel-Rahman, Hamdy; Fournier-Dit-Chabert, Jérémie; Shnyder, Steven D.; Loadman, Paul M.; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC ; Burns, Philip A.; Pors, Klaus | artículo |
closedAccess | | 15-dic-2012 | Synthesis and biological evaluation of colchicine C-ring analogues tethered with aliphatic linkers suitable for prodrug derivatisation | Fournier-Dit-Chabert, Jérémie; Vinader, Victoria; Santos, Ana Rita; Redondo-Horcajo, Mariano CSIC ORCID ; Dreneau, Aurore; Basak, Ramkrishna; Cosentino, Laura; Marston, Gemma; Abdel-Rahman, Hamdy; Loadman, Paul M.; Shnyder, Steven D.; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC ; Falconer, Robert A.; Pors, Klaus | artículo |
closedAccess | | 24-nov-2014 | Synthesis and biological evaluation of new oxadiazoline-substituted naphthalenyl acetates as anticancer agents | Chaaban, Ibrahim; El Khawass, El Sayeda M.; Abd El Razik, Heba A.; El Salamouni, Nehad S.; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Yli-Kauhaluoma, Jari; Moreira, Vânia M. | artículo |
closedAccess | | 2013 | Synthesis and biological evaluation of truncated α-tubulin-binding pironetin analogues lacking alkyl pendants in the side chain or the dihydropyrone ring | Paños, Julián; Díaz-Oltra, Santiago; Sánchez-Peris, María; García-Pla, Jorge; Murga, Juan; Falomir, Eva; Carda, Miguel; Redondo-Horcajo, Mariano CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC ; Marco, J. Alberto | artículo |
openAccess | | 2023 | Synthesis and structure-activity relationship studies of C(13)-desmethylene-(−)-zampanolide analogs | Brütsch, Tobias M.; Cotter, Etienne; Lucena-Agell, Daniel CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Davies, Carolina; Pfeiffer, Bernhard; Pagani, Sandro; Berardozzi, Simone; Díaz, José Fernando CSIC ORCID ; Miller, John H.; Altmann, Karl-Heinz | artículo |
openAccess | | 5-mar-2019 | Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate | Gaugaz, Fabienne Z.; Chicca, Andrea; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz | artículo |
closedAccess | | 3-abr-2019 | Synthesis, profiling, and bioactive conformation of trans-Cyclopropyl Epothilones | Kuzniewski, Christian N.; Glauser, Simon; Gaugaz, Fabienne Z.; Schiess, Raphael; Rodríguez-Salarichs, Javier CSIC; Vetterli, Stefan; Horlacher, Oliver P.; Gertsch, Jürg; Redondo-Horcajo, Mariano CSIC ORCID ; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz | artículo |
openAccess | | nov-2023 | Tannic Acid and Ethyl Gallate Potentialize Paclitaxel Effect on Microtubule Dynamics in Hep3B Cells | Sánchez-Carranza, Jessica Nayelli; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Escobar-Aguilar, Ever Angel; Millán-Pacheco, César; Álvarez, Laura CSIC ORCID; Salas-Vidal, Enrique; Díaz, José Fernando CSIC ORCID ; González-Maya, Leticia | artículo |
closedAccess | | oct-2014 | The impact of cyclopropane configuration on the biological activity of cyclopropyl-epothilones | Gaugaz, Fabienne Z.; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Cobos-Correa, Amanda; Kaufmann, Markus; Altmann, Karl-Heinz | artículo |
closedAccess | | ago-2015 | The Mechanism of the Interactions of Pironetin Analog/Combretastatin A-4 Hybrids with Tubulin | Torijano-Gutiérrez, Sandra; Vilanova, Concepción; Díaz-Oltra, Santiago; Murga, Juan; Falomir, Eva; Carda, Miguel; Redondo-Horcajo, Mariano CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC ; Marco, J. Alberto | artículo |