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openAccessJ. Biol. Chem.-2003-Fernández-Tornero-21774-81.pdf.jpg13-jun-2003Leads for development of new naphthalenesulfonate derivatives with enhanced antiangiogenic activity: crystal structure of acidic fibroblast growth factor in complex with 5-amino-2-naphthalene sulfonateFernández-Tornero, Carlos CSIC ORCID ; Lozano, R.M. CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Gómez, Ana M. CSIC ORCID ; López, José C.; Quesada, Ernesto CSIC ORCID ; Uriel, Clara CSIC ORCID; Valverde, Serafín; Romero, Antonio CSIC ORCID ; Giménez-Gallego, Guillermo CSICartículo
openAccess2017 Tang et al.pdf.jpg3-jun-2017Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions.Tang, Yong; Rodríguez-Salarichs, Javier CSIC; Estévez-Gallego, Juan CSIC ORCID ; Balaguer, Francisco de Asís CSIC ORCID; Redondo-Horcajo, Mariano CSIC ORCID ; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuoartículo
openAccessJ. Biol. Chem.-2001-Lozano.pdf.jpg21-sep-2001Solution structure and interaction with basic and acidic fibroblast growth factor of a 3-kDa human platelet factor-4 fragment with antiangiogenic activityLozano, R.M. CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Jiménez, M. Angeles CSIC ORCID ; Zilberberg, Lior; Cuevas, Pedro; Bikfalvi, Andreas; Rico, Manuel CSIC; Giménez-Gallego, Guillermo CSICartículo
closedAccessaccesoRestringido.pdf.jpg12-ago-2016Structural and Biochemical Characterization of the Interaction of Tubulin with Potent Natural Analogues of PodophyllotoxinAntúnez-Mojica, Mayra; Rodríguez-Salarichs, Javier CSIC; Redondo-Horcajo, Mariano CSIC ORCID ; León, Alejandra; Barasoain, Isabel CSIC ; Canales, Ángeles CSIC ORCID; Cañada, F. Javier ; Jiménez-Barbero, Jesús CSIC ORCID; Álvarez, Laura CSIC ORCID; Díaz, José Fernando CSIC ORCID artículo
openAccesschembiochem_prota_2017.pdf.jpg16-feb-2017Structural basis of microtubule stabilization by discodermolideProta, Andrea E.; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Smith III, Amos B.; Yang, Chia-Ping H.; McDaid, Hayley M.; Paterson, Ian; Horwitz, Susan; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.artículo
openAccessacsomega_trigili_2016.pdf.jpg13-dic-2016Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer CellsTrigili, Chiara CSIC; Barasoain, Isabel CSIC ; Sánchez-Murcia, Pedro A. CSIC ORCID; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Nogales, Aurora CSIC ORCID; Gardner, Nicola M.; Meyer, Arndt; Naylor, Guy J.; Gomez-Rubio, Elena CSIC ORCID; Gago, Federico CSIC ORCID; Steinmetz, Michel O.; Paterson, Ian; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpgsep-2016Synthesis and Anti-Proliferative Activity of Sulfanyltriazolylnaphthalenols and Sulfanyltriazolylnaphthalene-1,4-dionesChaaban, Ibrahim; El Khawass, El Sayeda M.; Abd El Razik, Heba A.; El Salamouni, Nehad S.; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Yli-Kauhaluoma, Jari; Moreira, Vânia M.artículo
closedAccessaccesoRestringido.pdf.jpg28-feb-2013Synthesis and biological evaluation as microtubule-active agents of several tetrahydrofuran and spiroacetal derivativesCarda, Miguel; Murga, Juan; Paños, Julián; Angulo-Pachón, C.A.; García-Pla, Jorge; Díaz-Oltra, Santiago; Marco, J. Alberto; Trigili, Chiara CSIC; Redondo-Horcajo, Mariano CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC artículo
closedAccessrestringido.pdf.jpg2012Synthesis and Biological Evaluation of Colchicine B‑Ring Analogues Tethered with Halogenated Benzyl MoietiesCosentino, Laura; Redondo-Horcajo, Mariano CSIC ORCID ; Zhao, Ying; Santos, Ana Rita; Chowdury, Kaniz F.; Vinader, Victoria; Abdallah, Qasem M. A.; Abdel-Rahman, Hamdy; Fournier-Dit-Chabert, Jérémie; Shnyder, Steven D.; Loadman, Paul M.; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC ; Burns, Philip A.; Pors, Klausartículo
closedAccessrestringido.pdf.jpg15-dic-2012Synthesis and biological evaluation of colchicine C-ring analogues tethered with aliphatic linkers suitable for prodrug derivatisationFournier-Dit-Chabert, Jérémie; Vinader, Victoria; Santos, Ana Rita; Redondo-Horcajo, Mariano CSIC ORCID ; Dreneau, Aurore; Basak, Ramkrishna; Cosentino, Laura; Marston, Gemma; Abdel-Rahman, Hamdy; Loadman, Paul M.; Shnyder, Steven D.; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC ; Falconer, Robert A.; Pors, Klausartículo
closedAccessaccesoRestringido.pdf.jpg24-nov-2014Synthesis and biological evaluation of new oxadiazoline-substituted naphthalenyl acetates as anticancer agentsChaaban, Ibrahim; El Khawass, El Sayeda M.; Abd El Razik, Heba A.; El Salamouni, Nehad S.; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Yli-Kauhaluoma, Jari; Moreira, Vânia M.artículo
closedAccessaccesoRestringido.pdf.jpg2013Synthesis and biological evaluation of truncated α-tubulin-binding pironetin analogues lacking alkyl pendants in the side chain or the dihydropyrone ringPaños, Julián; Díaz-Oltra, Santiago; Sánchez-Peris, María; García-Pla, Jorge; Murga, Juan; Falomir, Eva; Carda, Miguel; Redondo-Horcajo, Mariano CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC ; Marco, J. Albertoartículo
openAccessChemistry A European J_ Brütsch_2023.pdf.jpg2023Synthesis and structure-activity relationship studies of C(13)-desmethylene-(−)-zampanolide analogsBrütsch, Tobias M.; Cotter, Etienne; Lucena-Agell, Daniel CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Davies, Carolina; Pfeiffer, Bernhard; Pagani, Sandro; Berardozzi, Simone; Díaz, José Fernando CSIC ORCID ; Miller, John H.; Altmann, Karl-Heinzartículo
openAccessijms-20-01113.pdf.jpg5-mar-2019Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide ConjugateGaugaz, Fabienne Z.; Chicca, Andrea; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinzartículo
closedAccessrestringido.pdf.jpg3-abr-2019Synthesis, profiling, and bioactive conformation of trans-Cyclopropyl EpothilonesKuzniewski, Christian N.; Glauser, Simon; Gaugaz, Fabienne Z.; Schiess, Raphael; Rodríguez-Salarichs, Javier CSIC; Vetterli, Stefan; Horlacher, Oliver P.; Gertsch, Jürg; Redondo-Horcajo, Mariano CSIC ORCID ; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinzartículo
openAccessnov-2023Tannic Acid and Ethyl Gallate Potentialize Paclitaxel Effect on Microtubule Dynamics in Hep3B CellsSánchez-Carranza, Jessica Nayelli; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Escobar-Aguilar, Ever Angel; Millán-Pacheco, César; Álvarez, Laura CSIC ORCID; Salas-Vidal, Enrique; Díaz, José Fernando CSIC ORCID ; González-Maya, Leticiaartículo
closedAccessaccesoRestringido.pdf.jpgoct-2014The impact of cyclopropane configuration on the biological activity of cyclopropyl-epothilonesGaugaz, Fabienne Z.; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Cobos-Correa, Amanda; Kaufmann, Markus; Altmann, Karl-Heinzartículo
closedAccessaccesoRestringido.pdf.jpgago-2015The Mechanism of the Interactions of Pironetin Analog/Combretastatin A-4 Hybrids with TubulinTorijano-Gutiérrez, Sandra; Vilanova, Concepción; Díaz-Oltra, Santiago; Murga, Juan; Falomir, Eva; Carda, Miguel; Redondo-Horcajo, Mariano CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC ; Marco, J. Albertoartículo