Mostrando resultados 6 a 18 de 18
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Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
closedAccess | | 1-jun-2011 | Mecanismo de accion de los macrolidos citotoxicos amphinolidas X y J | Trigili, Chiara CSIC; Pera, Benet CSIC; Barbazanges, Marion; Cossy, Janine; Meyer, Christophe; Pineda, Oriol; Rodríguez-Escrich, Carles; Urpí, Félix; Vilarrasa, Jaume; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC | póster de congreso |
closedAccess | | 2-may-2011 | Mechanism of Action of Cytotoxic Macrolides Amphidinolide X and J. | Trigili, Chiara CSIC; Pera, Benet CSIC; Barbazanges, Marion; Cossy, Janine; Meyer, Christophe; Pineda, Oriol; Rodríguez-Escrich, Carles; Urpí, Félix; Vilarrasa, Jaume; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC | artículo |
openAccess | | 21-dic-2011 | Modulation of microtubule interprotofilament interactions by modified taxanes | Matesanz, Ruth CSIC ; Rodríguez-Salarichs, Javier CSIC; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCID; Bras, Wim; Nogales, Aurora CSIC ORCID; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID | artículo |
closedAccess | | 16-ago-2010 | Molecular recognition of peloruside A by microtubules. The C24 primary alcohol is essential for biological activity. | Pera, Benet CSIC; Razzak, Mina; Trigili, Chiara CSIC; Pineda, Oriol; Canales, Ángeles CSIC ORCID; Martínez Buey, Rubén CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Paterson, Ian; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID | artículo |
closedAccess | | 16-jul-2013 | New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism | Pera, Benet CSIC; Barasoain, Isabel CSIC ; Pantazopoulou, Areti CSIC ORCID; Canales, Ángeles CSIC ORCID; Matesanz, Ruth CSIC ; Rodríguez-Salarichs, Javier CSIC; García-Fernández, Luis F. CSIC; Moneo, Victoria; Jiménez-Barbero, Jesús CSIC ORCID; Galmarini, Carlos M.; Cuevas, Carmen; Peñalva, Miguel Ángel CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Andreu, José Manuel CSIC ORCID | artículo |
closedAccess | | 1-abr-2014 | PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors | Martínez-Díez, Marta; Guillén-Navarro, María José; Pera, Benet CSIC; Bouchet, Benjamin Pierre; Martínez-Leal, Juan Fernando; Barasoain, Isabel CSIC ; Cuevas, Carmen; Andreu, José Manuel CSIC ORCID ; García-Fernández, Luis F. CSIC; Díaz, José Fernando CSIC ORCID ; Avilés, Pablo; Galmarini, Carlos M. | artículo |
openAccess | | 2011 | Shotgun and targeted MS analyses pinpoint the zampanolide-tubulin interacting site | Calvo, Enrique; Field, Jessica J.; Pera, Benet CSIC; Zuwerra, D.; López, Juan Antonio; Camafeita, Emilio; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID | póster de congreso |
closedAccess | | nov-2012 | Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents | Milelli, Andrea; Tumiatti, Vicenzo; Micco, Marialuisa; Rosini, Michela; Zuccari, Guendalina; Raffaghello, Lizzia; Bianchi, Giovanna; Pistoia, Vito; Pistoia, Vito; Díaz, José Fernando CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Pera, Benet CSIC; Trigili, Chiara CSIC; Barasoain, Isabel CSIC ; Musetti, Caterina; Toniolo, Marianna; Sissi. Claudia; Alcaro, Stefano; Moraca, Federica; Zini, Maddalena; Stefanelli, Claudio; Minarini, Anna | artículo |
openAccess | | 19-jun-2014 | Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances | Matesanz, Ruth CSIC ; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier CSIC; Pera, Benet CSIC; Jiménez-Barbero, Jesús CSIC ORCID; Canales, Ángeles CSIC ORCID; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID | artículo |
openAccess | | nov-2011 | Thermodynamics as a Tool for the Optimization of Drug Binding, Thermodynamics - Interaction Studies - Solids, Liquids and Gases | Matesanz, Ruth CSIC ; Pera, Benet CSIC; Díaz, José Fernando CSIC ORCID | capítulo de libro |
closedAccess | | 1-jun-2011 | Zampanolida, un novedoso agente estabilizador de microtubulos quew se une covalentemente al sitio de paclitaxel | Field, Jessica J.; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Zuwerra, D.; Trigili, Chiara CSIC; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Miller, J.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID | póster de congreso |
openAccess | | 12-oct-2017 | Zampanolide binding to tubulin indicates crosstalk of taxane site with colchicine and nucleotide sites | Field, Jessica J.; Pera, Benet CSIC; Estévez-Gallego, Juan CSIC ORCID ; Rodríguez-Salarichs, Javier CSIC; Sáez-Calvo, Gonzalo CSIC; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID | artículo |
openAccess | | 22-jun-2012 | Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubules | Field, Jessica J.; Pera, Benet CSIC; Calvo, Enrique; Canales, Ángeles CSIC ORCID; Zurwerra, Didier; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier CSIC; Matesanz, Ruth CSIC ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID | artículo |