Mostrando resultados 3 a 22 de 54
< Anterior
Siguiente >
| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| closedAccess |  | 2018 | Contilisant, a Tetratarget Small Molecule for Alzheimer's Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile | Bautista-Aguilera, Óscar M. CSIC ORCID; Budni, J.; Mina, F.; Medeiros, E. B.; Deuther-Conrad, W.; Entrena, J. M.; Moraleda, I.; Iriepa, Isabel; López-Muñoz, Francisco; Marco-Contelles, José CSIC ORCID | artículo |
| closedAccess |  | 2014 | Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease | Bautista-Aguilera, Óscar M. CSIC ORCID; Esteban, Gerard; Bolea, Irene; Nikolic, Katarina; Agbaba, Danica; Moraleda, Ignacio; Iriepa, Isabel; Samadi, Abdelouahid CSIC ORCID; Soriano, Elena CSIC; Unzeta, Mercedes; Marco-Contelles, José CSIC ORCID | artículo |
| openAccess |  | 2019 | Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy | Pachón-Angona, I.; Refouvelet, B.; Andrys, R.; Martin, Hélène; Luzet, V.; Iriepa, Isabel; Moraleda, I.; Diez-Iriepa, Daniel CSIC; Oset-Gasque, María Jesús; Marco-Contelles, José CSIC ORCID; Musilek, K.; Ismaili, L. | artículo |
| closedAccess |  | 2014 | Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease | Wang, L.; Esteban, Gerard; Ojima, Masaki; Bautista-Aguilera, Óscar M. CSIC ORCID; Inokuchi, Tsutomu; Moraleda, Ignacio; Iriepa, Isabel; Samadi, Abdelouahid CSIC ORCID; Youdim, Moussa B. H.; Romero Jódar, Alejandro CSIC ORCID; Soriano, Elena CSIC; Herrero-Labrador, Raquel CSIC ORCID; Fernández Fernández, Ana Patricia CSIC; Martínez-Murillo, Ricardo CSIC ORCID; Marco-Contelles, José CSIC ORCID; Unzeta, Mercedes | artículo |
| openAccess |  | 4-jun-2023 | Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer’s Disease Treatment | Dakhlaoui, I.; Bernard, P. J.; Pietrzak, Diana; Simakov, Alexey; Maj, Maciej; Refouvelet, Bernard; Béduneau, Arnaud; Cornu, Raphaël; Józwiak, K.; Chabchoub, Fakher; Iriepa, Isabel; Martin, Hélène; Marco-Contelles, José CSIC ORCID; Ismaili, Lhassane | artículo |
| openAccess |  | 24-mar-2016 | Imidazopyranotacrines as Non-Hepatotoxic, Selective Acetylcholinesterase Inhibitors, and Antioxidant Agents for Alzheimer's Disease Therapy | Boulebd, Houssem; Ismaili, L.; Bartolini, Manuela; Bouraiou, Abdelmalek; Andrisano, Vincenza; Martin, Hélène; Bonet, Alexandre; Moraleda, Ignacio; Iriepa, Isabel; Chioua, Mourad CSIC ORCID ; Belfaitah, Ali; Marco-Contelles, José CSIC ORCID | artículo |
| closedAccess |  | 1-jun-2003 | Infrared analysis and molecular structure of α-aminonitriles derived from 1-azaadamantan-4-one | Iriepa, Isabel; Villasante, Francisco Javier; Morreale, Antonio; Gálvez-Ruano, Enrique; Bellanato, Juana CSIC ; Cano, Félix H. | artículo |
| closedAccess |  | 2019 | Multi-target 1,4-dihydropyridines showing calcium channel blockade and antioxidant capacity for Alzheimer's disease therapy | Malek, R.; Maj, M.; Wnorowski, A.; Józwiak, K.; Martin, Helene; Iriepa, Isabel; Moraleda, I.; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, L. | artículo |
| openAccess |  | 2014 | Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: Design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids | Bautista-Aguilera, Óscar M. CSIC ORCID; Esteban, Gerard; Chioua, Mourad CSIC ORCID ; Nikolic, Katarina; Agbaba, Danica; Moraleda, Ignacio; Iriepa, Isabel; Soriano, Elena CSIC; Samadi, Abdelouahid CSIC ORCID; Unzeta, Mercedes; Marco-Contelles, José CSIC ORCID | artículo |
| closedAccess |  | 2017 | Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases | Bautista-Aguilera, Óscar M. CSIC ORCID; Hagenow, S.; Palomino-Antolín, Alejandra; Farré-Alins, V.; Ismaili, L.; Joffrin, P. L.; Jimeno, M. Luisa CSIC ORCID; Soukup, Ondrej; Janockova, Jana; Kalinowski, A.; Proschak, E.; Iriepa, Isabel; Moraleda, I.; Schwed, J. S.; Romero Jódar, Alejandro CSIC ORCID; López-Muñoz, Francisco; Chioua, Mourad CSIC ORCID ; Egea, Javier; Ramsay, R. R.; Marco-Contelles, José CSIC ORCID; Stark, H. | artículo |
| closedAccess |  | 2019 | Novel Quinolylnitrones Combining Neuroprotective and Antioxidant Properties | Chioua, Mourad CSIC ORCID ; Salgado-Ramos, M.; Diez-Iriepa, Daniel CSIC; Escobar-Peso, Alejandro CSIC ORCID; Iriepa, Isabel; Hadjipavlou-Litina, Dimitra; Martínez-Alonso, Emma; Alcázar, Alberto; Marco-Contelles, José CSIC ORCID | artículo |
| openAccess; openAccess |  | 2022 | Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment | Diez-Iriepa, Daniel CSIC; Knez, Damijan; Gobec, Stanislav; Iriepa, Isabel; de los Ríos, Cristóbal; Bravo, I.; López-Muñoz, Francisco; Marco-Contelles, José CSIC ORCID; Hadjipavlou-Litina, Dimitra | artículo |
| closedAccess |  | 2016 | Potent anticholinesterasic and neuroprotective pyranotacrines as inhibitors of beta-amyloid aggregation, oxidative stress and tau-phosphorylation for Alzheimer's disease | García-Font, Nuria; Hayour, H.; Belfaitah, A.; Pedraz, J.; Moraleda, I.; Iriepa, Isabel; Bouraiou, A.; Chioua, Mourad CSIC ORCID ; Marco-Contelles, José CSIC ORCID; Oset-Gasque, María Jesús | artículo |
| closedAccess |  | 2015 | Pyranopyrazolotacrines as nonneurotoxic, Aβ-anti-aggregating and neuroprotective agents for Alzheimer's disease | Chioua, Mourad CSIC ORCID ; Pérez-Peña, Javier; García-Font, Nuria; Moraleda, Ignacio; Iriepa, Isabel; Soriano, Elena CSIC; Marco-Contelles, José CSIC ORCID; Oset-Gasque, María Jesús | artículo |
| openAccess |  | 17-abr-2019 | QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer’s Disease Therapy | Ramos, Eva; Palomino-Antolín, Alejandra; Bartolini, Manuela; Iriepa, Isabel; Moraleda, Ignacio; Diez-Iriepa, Daniel CSIC; Samadi, Abdelouahid CSIC ORCID; Cortina, Carol V.; Chioua, Mourad CSIC ORCID ; Egea, Javier; Romero Jódar, Alejandro CSIC ORCID; Marco-Contelles, José CSIC ORCID | artículo |
| closedAccess |  | 28-may-2001 | Spectroscopic study of 3-methyl-3-azabicyclo[3.2.1]octan-8α (and β)-ols | Iriepa, Isabel; Herranz, Maria José; Gálvez-Ruano, Enrique; Bellanato, Juana CSIC | artículo |
| openAccess |  | 2023 | Straightforward Synthesis of Bis[(trifluoromethyl)sulfonyl]ethylated Isocoumarins from 2-Ethynylbenzoates | Petcu, Sonia A. CSIC; Lázaro-Milla, Carlos; Rodríguez, Francisco Javier; Iriepa, Isabel; Bautista-Aguilera, Óscar M. CSIC ORCID; Aragoncillo, Cristina CSIC ORCID; Alonso, José M. CSIC; Almendros, Pedro CSIC ORCID | artículo |
| closedAccess |  | 1993 | Structural and conformational study of 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9α-ol | Iriepa, Isabel; Sanz-Aparicio, J. CSIC ORCID; Fonseca, Isabel M.; Bellanato, Juana CSIC | artículo |
| closedAccess |  | 1993 | Structural study of 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9β- ol | Iriepa, Isabel; Gil-Alberdi, B.; Gálvez-Ruano, Enrique; Torres, R.; Gómez-Sal, Pilar; Bellanato, Juana CSIC | artículo |
| closedAccess |  | 1-jun-2003 | Structural study of 3-methyl-3-azabicyclo[3.2.1]octan-8α(and β)-ols by ab initio calculations, NMR and IR spectroscopy | Iriepa, Isabel; Madrid, A. I.; Morreale, Antonio; Gálvez-Ruano, Enrique; Bellanato, Juana CSIC | artículo |
