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closedAccessaccesoRestringido.pdf.jpg8-nov-2011Acid sphingomyelinase is required for chronic alcohol-induced steatosis, ER stress and LPS susceptibilityFernández, Anna; Matías, Nuria CSIC; Fucho, Raquel CSIC ORCID; Nuño-Lámbarri, Natalia; Bataller, Ramón; Dubuquoy, Laurent; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDpóster de congreso
closedAccessaccesoRestringido.pdf.jpgabr-2011Acidic sphingomyelinase controls diet-induced insulin sensitivity, adipose tissue homeostasis and hepatic steatosisFucho, Raquel CSIC ORCID; Balgoma, David CSIC ORCID; Balsinde, Jesús CSIC ORCID ; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID comunicación de congreso
openAccessASMase.pdf.jpg2013ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loadingFernández, Anna; Matías, Nuria CSIC; Fucho, Raquel CSIC ORCID; Ribas, Vicent CSIC ORCID; Montfort, Claudia von CSIC; Nuño-Lámbarri, Natalia; Baulies, Anna CSIC ORCID; Martínez, Laura CSIC; Tarrats, Núria CSIC; Marí, Montserrat CSIC ORCID ; Colell Riera, Anna CSIC ORCID; Morales, Albert CSIC ORCID; Bataller, Ramón; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpgnov-2014ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitisFucho, Raquel CSIC ORCID; Martínez, Laura CSIC; Baulies, Anna CSIC ORCID; Torres, Sandra CSIC ORCID; Tarrats, Núria CSIC; Fernández, Anna; Ribas, Vicent CSIC ORCID; Astudillo, Alma M. CSIC ORCID; Balsinde, Jesús CSIC ORCID ; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpgabr-2017Ceramides and mitochondrial fatty acid oxidation in obesityFucho, Raquel CSIC ORCID; Casals, Núria; Serra, Dolors; Herrero, Laura CSIC ORCIDartículo
openAccessCholesterolenrichme_Solsona.pdf.jpgjun-2019Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexesSolsona-Vilarrasa, Estel CSIC ORCID; Fucho, Raquel CSIC ORCID; Torres, Sandra CSIC ORCID; Nuñez, Susana CSIC; Nuño-Lámbarri, Natalia; Enrich, Carlos; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg9-nov-2018Cholesterol loading in liver mitochondria alters mitochondrial morphology, respiration and respiratory supercomplexes assemblySolsona-Vilarrasa, Estel CSIC ORCID; Fucho, Raquel CSIC ORCID; Torres, Sandra CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDcomunicación de congreso
closedAccessaccesoRestringido.pdf.jpg9-nov-2018Chronic alcohol feeding increases mitochondrial respiration in frg mice with humanized liverInsausti, Naroa CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Fucho, Raquel CSIC ORCID; Torres, Sandra CSIC ORCID; Alarcón-Vila, Cristina CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDpóster de congreso
openAccess1-s2.0-S2213231722003688-main.pdf.jpgfeb-2023Dietary and genetic disruption of hepatic methionine metabolism induce acid sphingomyelinase to promote steatohepatitisAlarcón-Vila, Cristina CSIC ORCID; Insausti, Naroa CSIC ORCID; Torres, Sandra CSIC ORCID; Segalés, Paula CSIC; Conde de la Rosa, Laura CSIC ORCID ; Nuñez, Susana CSIC; Fucho, Raquel CSIC ORCID; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID artículo
openAccess25-nov-2019Dietary cholesterol and overfeeding synergistically induce NASH and hepatocellular carcinoma in miceRobles, David CSIC; Vallejo, Carmen CSIC; Moles, Anna CSIC ORCID; Nuñez, Susana CSIC; Fucho, Raquel CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Insausti, Naroa CSIC ORCID; Ribas, Vicent CSIC ORCID; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID póster de congreso
closedAccessaccesoRestringido.pdf.jpgago-2010Differential hepatic lipid accumulation in ASMase−/− mice on HFD is associated with hyperglycaemia and liver damageFucho, Raquel CSIC ORCID; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDcomunicación de congreso
openAccessantioxidants-09-01063.pdf.jpg30-oct-2020Disrupted Mitochondrial and Metabolic Plasticity Underlie Comorbidity between Age-Related and Degenerative Disorders as Parkinson Disease and Type 2 Diabetes MellitusJuárez-Flores, Diana-Luz; Ezquerra, Mario; González-Casacuberta, Ingrid; Ormazabal, Aida; Morén, Constanza; Tolosa, Eduardo; Fucho, Raquel CSIC ORCID; Guitart-Mampel, Mariona; Casado, Mercedes; Valldeoriola, Francesc; Torre-Lara, Joan de la; Muñoz, Esteban; Tobías Rossell, Ester; Compta, Yaroslau; García-García, Francesc Josep; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCID; Martí, María-José; Grau-Junyent, Josep María; Cardellach, Francesc; Artuch, Rafael; Fernández-Santiago, Rubén; Garrabou, Glòriaartículo
openAccessEndoplasmic Reticulum_Torres.pdf.jpgago-2019Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver FailureTorres, Sandra CSIC ORCID; Baulies, Anna CSIC ORCID; Insausti, Naroa CSIC ORCID; Alarcón-Vila, Cristina CSIC ORCID; Fucho, Raquel CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Nuñez, Susana CSIC; Robles, David CSIC; Ribas, Vicent CSIC ORCID; Wakefield, Leslie; Grompe, Markus; Lucena, M. Isabel; Andrade, Raúl J.; Win, Sanda; Aung, Tin; Kaplowitz, Neil; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
openAccessHernandez S. GDF11 restricts aberrant lipogenesis and changes in mitocho....pdf.jpgmay-2021GDF11 restricts aberrant lipogenesis and changes in mitochondrial structure and function in human hepatocellular carcinoma cellsHernández-Rizo, Sharik; Simoni-Nieves, Arturo; Gerardo-Ramírez, Montserrat; Torres, Sandra CSIC ORCID; Fucho, Raquel CSIC ORCID; Gonzalez, Jonathan; Castellanos‐Tapia, Lyssia; Hernández‐Pando, Rogelio; Tejero‐Barrera, Elizabeth; Bucio, Leticia; Souza, Verónica; Miranda‐Labra, Roxana; Fernández-Checa, José C. CSIC ORCID; Marquardt, Jens U.; Gómez-Quiroz, Luís Enrique; García-Ruiz, Carmen CSIC ORCID ; Gutiérrez-Ruiz, María Concepciónartículo
openAccessfj.202000678R.pdf.jpg15-jul-2020Liver CPT1A gene therapy reduces diet‐induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLDWeber, Minéia; Mera, Paula; Casas, Josefina CSIC ORCID ; Salvador, Javier; Rodríguez, Amaia; Alonso, Sergio; Sebastián, David; Soler‐Vázquez, M. Carmen; Montironi, Carla; Recalde, Sandra; Fucho, Raquel CSIC ORCID; Calderón‐Domínguez, María; Mir, Joan Francesc; Bartrons, Ramón; Escolà-Gil, Joan Carles; Sánchez‐Infantes, David; Zorzano, Antonio; Llorente-Cortés, Vicenta CSIC ORCID; Casals, Núria; Valentí, Víctor; Frühbeck, Gema; Herrero, Laura CSIC ORCID; Serra, Dolorsartículo
openAccess9-jun-2019Mitochondrial and autophagic alterations in skin fibroblasts from Parkinson disease patients with Parkin mutationsGonzález-Casacuberta, Ingrid; Juárez-Flores, Diana-Luz; Ezquerra, Mario; Fucho, Raquel CSIC ORCID; Catalán-García, Marc; Guitart-Mampel, Mariona; Tobías Rossell, Ester; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCID; Tolosa, Eduardo; Martí, María-José; Grau-Junyent, Josep María; Fernández-Santiago, Rubén; Cardellach, Francesc; Morén, Constanza; Garrabou, Glòriaartículo
closedAccessaccesoRestringido.pdf.jpg8-nov-2011Mitochondrial gsh determines the toxic or therapeutic potential of superoxide anion scavenging in nonalcoholic steatohepatitisMatías, Nuria CSIC; Montfort, Claudia von CSIC; Fernández, Anna; Fucho, Raquel CSIC ORCID; Martínez-Chantar, María Luz CSIC ORCID; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDpóster de congreso
openAccess2012Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitisMontfort, Claudia von CSIC; Matías, Nuria CSIC; Fernández, Anna; Fucho, Raquel CSIC ORCID; Conde de la Rosa, Laura CSIC ORCID ; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg30-may-2018Obesity-induced hepatic steatosis in mice is reverted by AAV9-mediated enhanced fatty-acid oxidationSerra, Dolors; Weber, Minéia; Casas, Josefina CSIC ORCID ; Sebastian, D.; Recalde, Sergio; Mir, Joan Francesc; Fucho, Raquel CSIC ORCID; Calderón‐Domínguez, María; Mera, Paula; Zagmutt, Sebastián; Soler-Vázquez, M. Carmen; Ibeas, Kevin; Escolà-Gil, Joan Carles; Llorente-Cortés, Vicenta CSIC ORCID; Casals, Núria; Zorzano, A.; Fabriàs, Gemma CSIC ORCID ; Herrero, Laura CSIC ORCIDcomunicación de congreso
openAccess2013Role of acid sphingomyelinase in steatohepatitisFucho, Raquel CSIC ORCIDtesis doctoral