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dc.contributor.authorMacchione, Giuseppe-
dc.contributor.authorde Paz, José L.-
dc.contributor.authorNieto, Pedro M.-
dc.date.accessioned2014-06-23T08:32:22Z-
dc.date.available2014-06-23T08:32:22Z-
dc.date.issued2014-
dc.identifier.citationCarbohydrate Research, 395: 17-25 (2014)es_ES
dc.identifier.urihttp://hdl.handle.net/10261/98747-
dc.description.abstractThe synthesis of hyaluronic acid oligomers (tri- and tetrasaccharide) is described. We have followed a pre-glycosylation oxidation strategy. Glucuronic acid units were directly employed in coupling reactions with suitably protected glucosamine derivatives. In order to simplify the purification of synthetic intermediates, a fluorous-assisted strategy has been also explored. Using this approach, a hyaluronic acid trisaccharide was prepared.es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.rightsopenAccesses_ES
dc.subjectHyaluronic acides_ES
dc.subjectGlycosylationes_ES
dc.subjectFluorous tages_ES
dc.subjectOligosaccharide synthesises_ES
dc.subjectGlucuronic acides_ES
dc.subjectCarbohydrateses_ES
dc.titleSynthesis of hyaluronic acid oligosaccharides and exploration of a fluorous-assisted approaches_ES
dc.typeartículoes_ES
dc.identifier.doi10.1016/j.carres.2014.05.007-
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1016/j.carres.2014.05.007es_ES
dc.relation.csices_ES
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