English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/98492
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

Mechanochemical synthesis and characterization of II-VI nanocrystals: Challenge for cytotoxicity issues

AutorBaláž , P.; Jardin, R.; Dutková, E.; Sayagués, María Jesús ; Baláž , M.; Moizis, J.; Turinicovña, E.; Fabián, M.
Fecha de publicación2012
EditorPolish Academy of Sciences
CitaciónActa Physica Polonica A 122: 224- 229 (2012)
ResumenCdSe@ZnS nanocrystals have been prepared by a two-step solid state mechanochemical synthesis. CdSe prepared from elements in the first step is mixed with ZnS synthesized from zinc acetate and sodium sulfide in the second step. The crystallite size of the new type CdSe@ZnS nanocrystals determined by X-ray diffraction Rietveld refined method was 35 nm and 10 nm for CdSe and ZnS, respectively. Energy dispersive/transmission electron microscopy/energy dispersive spectroscopy methods show good crystallinity of the nanoparticles and scanning electron microscopy elemental mapping illustrate consistent distribution of Cd, Se, Zn and S elements in the bulk of samples. UV-VIS spectra show an onset at 320 nm with calculated bandgap 3.85 eV. This absorption arises from the vibration modes of Zn-S bonds. The nanocrystals show the blue shift from the bandgap of bulk ZnS (3.66 eV). The synthesized CdSe@ZnS nanocrystals have been tested for dissolution, cytotoxicity and L-cysteine conjugation. The dissolution of Cd was less than 0.05 μg mL -1 (in comparison with 0.8 μg mL -1 which was evidenced for CdSe alone). The very low cytotoxic activity for selected cancer cell lines has been evidenced. CdSe@ZnS nanocrystals coated with L-cysteine are water-soluble and have a great potential in biomedical engineering as fluorescent labels.
URIhttp://hdl.handle.net/10261/98492
DOInull
Identificadoresdoi: null
issn: 0587-4246
Aparece en las colecciones: (ICMS) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
accesoRestringido.pdf15,38 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.