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Título

The others: our biased perspective of eukaryotic genomes

AutorCampo, Javier del ; Sieracki, Michael E.; Molestina, Robert; Keeling, Patrick; Massana, Ramon ; Ruiz-Trillo, Iñaki
Palabras claveCulture collections
Eukaryotic tree of life
Ecology
Culturing bias
Single cell genomics
Phylogeny
Eukaryotic genomics
Fecha de publicaciónmay-2014
EditorElsevier
CitaciónTrends in Ecology and Evolution 29(5): 252-259 (2014)
ResumenUnderstanding the origin and evolution of the eukaryotic cell and the full diversity of eukaryotes is relevant to many biological disciplines. However, our current understanding of eukaryotic genomes is extremely biased, leading to a skewed view of eukaryotic biology. We argue that a phylogeny-driven initiative to cover the full eukaryotic diversity is needed to overcome this bias. We encourage the community: (i) to sequence a representative of the neglected groups available at public culture collections, (ii) to increase our culturing efforts, and (iii) to embrace single cell genomics to access organisms refractory to propagation in culture. We hope that the community will welcome this proposal, explore the approaches suggested, and join efforts to sequence the full diversity of eukaryotes. © 2014 Elsevier Ltd.
Descripción8 pages, 4 figures, 1 appendix supplementary data associated with this article can be found, in the online version, at http://dx.doi.org/10.1016/j.tree.2014.03.006
Versión del editorhttp://dx.doi.org/10.1016/j.tree.2014.03.006
URIhttp://hdl.handle.net/10261/97562
DOI10.1016/j.tree.2014.03.006
Identificadoresdoi: 10.1016/j.tree.2014.03.006
issn: 0169-5347
e-issn: 1872-8383
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