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dc.contributor.authorSaugar, José María-
dc.contributor.authorAlarcón, Teresa-
dc.contributor.authorLópez-Hernández, Susana-
dc.contributor.authorLópez-Brea, Manuel-
dc.contributor.authorAndreu, David-
dc.contributor.authorRivas, Luis-
dc.date.accessioned2014-05-22T10:58:20Z-
dc.date.available2014-05-22T10:58:20Z-
dc.date.issued2002-03-
dc.identifier.citationAntimicrobial Agents and Chemotherapy 46 (3) 875- 878 (2002)-
dc.identifier.issn0066-4804-
dc.identifier.urihttp://hdl.handle.net/10261/97097-
dc.description.abstractPolymyxin B (PXB) and the cecropin A-melittin hybrid CA(1-8)M(1-18) (KWKLFKKIGIGAVLKVLTTGLPALIS-NH2) were compared for antibiotic activity on reference and multiresistant Acinetobacter baumannii strains. Significant differences for both peptides were observed on their inner membrane interaction and inhibition by environmental factors, supporting the use of CA(1-8)M(1-18) as a potential alternative to PXB against Acinetobacter.-
dc.description.sponsorshipThis work was supported by grants from CAM (08/0029/1998) and FIS (99/0025) to M.L.B. and L.R., CAM Programa de Grupos Estratégicos to L.R., and CERBA, Generalitat de Catalunya to D.A. T.A. is recipient of a CAM postdoctoral fellowship.-
dc.publisherAmerican Society for Microbiology-
dc.rightsopenAccess-
dc.titleActivities of polymyxin B and cecropin A-melittin peptide CA(1-8)M(1-18) against a multiresistant strain of Acinetobacter baumannii-
dc.typeartículo-
dc.identifier.doi10.1128/AAC.46.3.875-878.2002-
dc.relation.publisherversionhttp://dx.doi.org/10.1128/AAC.46.3.875-878.2002-
dc.date.updated2014-05-22T10:58:20Z-
dc.description.versionPeer Reviewed-
dc.language.rfc3066eng-
dc.identifier.pmid11850277-
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.openairetypeartículo-
item.grantfulltextnone-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
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