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http://hdl.handle.net/10261/97069
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Lasa, Íñigo | - |
dc.contributor.author | Toledo-Arana, Alejandro | - |
dc.contributor.author | Gingeras, Thomas R. | - |
dc.date.accessioned | 2014-05-22T08:07:42Z | - |
dc.date.available | 2014-05-22T08:07:42Z | - |
dc.date.issued | 2012-08-01 | - |
dc.identifier | doi: 10.4161/rna.21167 | - |
dc.identifier | issn: 1547-6286 | - |
dc.identifier | e-issn: 1555-8584 | - |
dc.identifier.citation | RNA Biology 9(8): 1039-1044 (2012) | - |
dc.identifier.uri | http://hdl.handle.net/10261/97069 | - |
dc.description.abstract | Analysis of bacterial transcriptomes have shown the existence of a genome-wide process of overlapping transcription due to the presence of antisense RNAs, as well as mRNAs that overlapped in their entire length or in some portion of the 5′- and 3′-UTR regions. The biological advantages of such overlapping transcription are unclear but may play important regulatory roles at the level of transcription, RNA stability and translation. In a recent report, the human pathogen Staphylococcus aureus is observed to generate genome-wide overlapping transcription in the same bacterial cells leading to a collection of short RNA fragments generated by the endoribonuclease III, RNase III. This processing appears most prominently in Gram-positive bacteria. The implications of both the use of pervasive overlapping transcription and the processing of these double stranded templates into short RNAs are explored and the consequences discussed. © 2012 Landes Bioscience. | - |
dc.description.sponsorship | This research was supported by grants ERA-NET Pathogenomics (PIM2010EPA-00606), BIO2008-05284-C02, BIO2011- 30503-C02 and BFU2011-23222 from Spanish Ministry of Economy and Competitiveness. | - |
dc.description.sponsorship | A.T.-A. is recipient of “Ramon y Cajal” contracts from the Spanish Ministry of Science and Innovation. This research was supported by grants ERA-NET Pathogenomics (PIM2010EPA-00606), BIO2008-05284-C02, BIO2011-30503-C02 and BFU2011-23222 from Spanish Ministry of Economy and Competitiveness | - |
dc.publisher | Landes Bioscience | - |
dc.relation.isversionof | Postprint | - |
dc.rights | openAccess | - |
dc.subject | Overlapping transcription | - |
dc.subject | RNase III | - |
dc.subject | RNA processing | - |
dc.subject | Bacteria | - |
dc.subject | Transcriptomes | - |
dc.title | An effort to make sense of antisense transcription in bacteria | - |
dc.type | artículo | - |
dc.identifier.doi | 10.4161/rna.21167 | - |
dc.relation.publisherversion | http://dx.doi.org/10.4161/rna.21167 | - |
dc.date.updated | 2014-05-22T08:07:42Z | - |
dc.description.version | Peer Reviewed | - |
dc.language.rfc3066 | eng | - |
dc.contributor.funder | Ministerio de Ciencia e Innovación (España) | - |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | - |
dc.identifier.funder | http://dx.doi.org/10.13039/501100004837 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003329 | es_ES |
dc.identifier.pmid | 22858676 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | With Fulltext | - |
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