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Title

Disturbance of erythrocyte lipid bilayer by amino acid-based surfactants

AuthorsMartínez, Verónica; Sánchez, Lourdes; Busquets, M. Antònia; Infante, María Rosa ; Vinardell, M. Pilar ; Mitjans, Montserrat
KeywordsPlasma membrane
Fluorescence anisotropy
Surfactants
Erythrocyte
Arginine
Lysine
Issue DateSep-2007
PublisherSpringer
CitationAmino Acids 33(3): 459-462 (2007)
AbstractIn an attempt to increase our knowledge regarding the mechanisms of surfactant membrane interaction, we studied the action of several anionic and cationic amino acid-based surfactants on membrane fluidity using fluorescence anisotropy. Anisotropy measurements demonstrated that almost all of the surfactants studied disturbed the external region of the erythrocyte membrane without affecting the core of the bilayer. How the physico-chemical properties and structure of these compounds affect dynamics of the lipid bilayer is discussed in detail.
Description4 pages, 2 tables.-- PMID: 17086480 [PubMed].-- Published online Nov 9, 2006.
Publisher version (URL)http://dx.doi.org/10.1007/s00726-006-0447-2
URIhttp://hdl.handle.net/10261/9704
DOIhttp://dx.doi.org/10.1007/s00726-006-0447-2
ISSN0939-4451
E-ISSN1438-2199
Appears in Collections:(IQAC) Artículos
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