In vitro bactericidal activity of the antiprotozoal drug miltefosine against Streptococcus pneumoniae and other pathogenic streptococci

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Título:	In vitro bactericidal activity of the antiprotozoal drug miltefosine against Streptococcus pneumoniae and other pathogenic streptococci
Autor:	Llull, Daniel ; Rivas, Luis ; García, Ernesto
Fecha de publicación:	may-2007
Editor:	American Society for Microbiology
Citación:	Antimicrobial Agents and Chemotherapy 51(5) 1844- 1848 (2007)
Resumen:	Miltefosine (hexadecylphosphocholine), the first oral drug against visceral leishmaniasis, triggered pneumococcal autolysis at concentrations higher than 2.5 μM. Bactericidal activity was also observed in cultures of other streptococci, although these failed to undergo lysis. The autolysis elicited by miltefosine can be attributed to triggering of the pneumococcal autolysin LytA. Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Versión del editor:	http://dx.doi.org/10.1128/AAC.01428-06
URI:	http://hdl.handle.net/10261/97029
DOI:	10.1128/AAC.01428-06
ISSN:	0066-4804
Aparece en las colecciones:	(CIB) Artículos

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