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Comparative study of the alpha-gliadin genes in diploid and polyploid genomes of wheat

AuthorsOzuna, Carmen CSIC ORCID; Giménez, María J. CSIC ORCID; Barro Losada, Francisco CSIC ORCID
KeywordsCeliac disease
Issue DateOct-2013
PublisherSociedad Española de Cultivo In Vitro de Tejidos Vegetales
Universidad de Zaragoza
CSIC - Estación Experimental de Aula Dei (EEAD)
CitationX Reunión de la SECIVTV (2013)
AbstractHexaploid bread wheat originated from the spontaneous hybridization of tetraploid wheat (Triticum turgidum, AABB) with a diploid progenitor, Aegilops tauschii (DD). The tetraploid wheat was from the hybridization of two diploid progenitors, Triticum urartu (AA) and an unconfirmed specie, which donated the BB genome. Gliadins are gluten proteins associated with celiac disease (CD), a food-sensitive enteropathy caused by the ingestion of gluten from wheat, barley and rye. The most toxic peptide is on an α-gliadin, which contains six overlapping T-cell epitopes with high stimulatory properties. The genes encoding α-gliadins are controlled by the Gli-2 loci (Gli-A2, Gli-B2, and Gli-D2) present on the short arms of the group 6 chromosomes in bread wheat. A collection of wheats encompassing the ancestor diploid genomes (AA, BB and DD) and the derived hexaploid (AABBDD) was studied to analyse the evolution of α-gliadin genes during the polyploidization phenomenon.
DescriptionPóster presentadao en la X Reunión de la SECIVTV, celebrada en Zaragoza del 22 al 24 de octubre de 2013.
Appears in Collections:(IAS) Comunicaciones congresos

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