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Title: | Single frequency impedimetric immunosensor for atrazine detection |
Authors: | Rodríguez, Ángel; Valera, Enrique; Ramón-Azcón, Javier ![]() ![]() ![]() |
Keywords: | Immunosensors Impedance spectroscopy Interdigitate μ-electrodes Atrazine |
Issue Date: | 22-Feb-2008 |
Publisher: | Elsevier |
Citation: | Sensor and Actuators B Chemical 129(2):921-928 (2007) |
Abstract: | A novel impedimetric immunosensor for the detection of a wide variety of compounds, based on a two coplanar non-passivated interdigitated metallic μ-electrodes and non-labeled immunoreactives, has been designed and developed. A very useful detection method is the impedance spectroscopy sweeping a wide frequency range. This is a powerful, but cumbersome tool to study the sensor performance providing trustworthy results. In this work, it is shown that the exploitation of the changes observed of the impedance at a single frequency provide very good correlation with antibody concentration and hence greatly reduces the signal acquisition and processing complexity. It has thereby a great potential for low cost, low power, fast response and simple use for the in-field or at-line applications. In this work, the application of the method to atrazine detection is described. The results show that the immunosensor signal is a function of the pesticide concentration following a competitive binding relationship, with limits of detection lower than the maximum residue level required by EC for atrazine in wine grapes and other foodstuff products. |
Description: | 8 pages, 8 figures.-- Available online on Oct 10, 2007. |
Publisher version (URL): | http://dx.doi.org/10.1016/j.snb.2007.10.003 |
URI: | http://hdl.handle.net/10261/9508 |
DOI: | 10.1016/j.snb.2007.10.003 |
ISSN: | 0925-4005 |
Appears in Collections: | (IQAC) Artículos |
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