English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/9507
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Citado 12 veces en Web of Knowledge®  |  Pub MebCentral Ver citas en PubMed Central  |  Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar otros formatos: Exportar EndNote (RIS)Exportar EndNote (RIS)Exportar EndNote (RIS)
Título

Synthesis and preliminary antifungal evaluation of a library of phytosphingolipid analogues

Autor Mormeneo, David; Casas Brugulat, Josefina; Llebaria, Amadeu; Delgado Cirilo, Antonio
Palabras clave Antifungal evaluation
Phytosphingolipid analogues
Growth inhibitors
Yeast Saccaromyces cerevisiae
Fecha de publicación 8-oct-2007
EditorRoyal Society of Chemistry (Great Britain)
Citación Organic & Biomolecular Chemistry 5(23): 3769-3777 (2007)
ResumenA library of 64 phytosphingolipid analogues resulting from the systematic variation of the C1, C3, C4, and the N-acyl moiety of phytosphingosine (PHS) has been prepared from common scaffolds derived from the chiral pool and Sharpless asymmetric dihydroxylation reactions. Library members have been evaluated as growth inhibitors of the yeast Saccaromyces cerevisiae. In addition, 1-amino-N-pivaloyl PHS analogues were also tested as IPC synthase inhibitors, in comparison with the natural product khafrefungin.
Descripción 9 pages, 4 figures.-- PMID: 18004456 [PubMed].
Versión del editorhttp://dx.doi.org/10.1039/b709421c
URI http://hdl.handle.net/10261/9507
DOI10.1039/b709421c
ISSN1477-0539
Aparece en las colecciones: (IQAC) Artículos
Ficheros en este ítem:
No hay ficheros asociados a este ítem.
Mostrar el registro completo
 



NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.