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Title

Bioactive polychlorinated bibenzyls from the liverwort Riccardia polyclada

AuthorsLabbé, Cecilia; Faini, Francesca; Villagrán, Carolina; Coll Toledano, Josep; Rycroft, David S.
KeywordsRiccardia polyclada
Chlorine atoms
Bibenzyl skeleton
Antifeedant activity
Issue Date20-Nov-2007
PublisherAmerican Chemical Society
American Society of Pharmacognosy
CitationJournal of Natural Products 70(12): 2019-2021 (2007)
AbstractGC-MS and 1H NMR spectroscopic profiling of a CDCl3 extract of the liverwort Riccardia polyclada (syn. R. umbrosa) revealed the presence of four main compounds bearing several chlorine atoms on a bibenzyl skeleton. Separation of a CH2Cl2 extract was achieved using preparative TLC, and structures 1–4 were proposed on the basis of spectroscopic evidence. Compounds 1–4 were active in a brine shrimp lethality bioassay (Artemia salina). In addition, 2 and 4 displayed moderate antifeedant activity in disk-choice bioassays with Spodoptera littoralis larvae and inhibited the growth of Cladosporium herbarum cultures on TLC plates.
Description3 pages, 2 tables.-- PMID: 18020419 [PubMed].-- Printed version published on Dec 28, 2007.
Publisher version (URL)http://dx.doi.org/10.1021/np070192c
URIhttp://hdl.handle.net/10261/9451
DOIhttp://dx.doi.org/10.1021/np070192c
ISSN0163-3864
E-ISSN1520-6025
Appears in Collections:(IQAC) Artículos
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