Genotoxicity of the insecticide rotenone in cultured human lymphocytes

Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/93728

COMPARTIR / EXPORTAR:

SHARE BASE	Comparte tu historia de Acceso Abierto
Visualizar otros formatos: MARC \| Dublin Core \| RDF \| ORE \| MODS \| METS \| DIDL \| DATACITE
Refman EndNote Bibtex RefWorks Excel CSV PDF DataCite Send via email

Título:	Genotoxicity of the insecticide rotenone in cultured human lymphocytes
Autor:	Guadaño-Ferraz, Ana CSIC ORCID ; González-Coloma, Azucena CSIC ORCID; Peña de Torres, Eduardo de la CSIC ORCID
Palabras clave:	Genotoxicity Micronucleus Rotenone Lymphocyte Natural insecticide
Fecha de publicación:	1998
Editor:	Elsevier
Citación:	Mutation Research 414: 1–7 (1998)
Resumen:	We have investigated the genotoxic activity of rotenone on three genetic endpoints, sister-chromatid exchanges (SCE), chromosome aberrations (CA)and micronuclei (MN) in human lymphocyte cultures in the presence and absence of a metabolic activation system (S9 mix). Our results indicate that rotenone increases the frequency of binucleated micronucle- ated (BNMN)cells and causes a delay in the cell cycle but does not increase the frequency of CA and SCE at the concentrations used. The presence of S9 mix reduces the genotoxic activity of rotenone.
Descripción:	7 páginas y 6 tablas estadísticas
URI:	http://hdl.handle.net/10261/93728
Aparece en las colecciones:	(ICA) Artículos