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Semisynthetic peptide-lipase conjugates for improved biotransformations

AuthorsRomero, Óscar; Filice, Marco ; Rivas, Blanca de las ; Carrasco-López, César ; Klett, Javier ; Morreale, Antonio ; Hermoso, Juan A. ; Guisán, José Manuel ; Abian, Olga ; Palomo, José Miguel
Issue Date2012
PublisherRoyal Society of Chemistry (UK)
CitationChemical Communications 48: 9053- 9055 (2012)
AbstractAn efficient chemoselective method for the creation of semisynthetic lipases by site-specific incorporation of tailor-made peptides on the lipase-lid site was developed. These new enzymes showed excellent improved specificity and regio- or enantioselectivity in different biotransformations. © 2012 The Royal Society of Chemistry.
Identifiersdoi: 10.1039/c2cc34816k
issn: 1359-7345
Appears in Collections:(ICTAN) Artículos
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