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Título: | Coexistence of Granulomatous Enteric Inflammation and Neoplasia in an Adult Sheep |
Autor: | Benavides, Julio CSIC ORCID ; García Pariente, C.; Garrido, J. M.; Sevilla, Iker A.; García Marín, Juan Francisco CSIC ; Pérez Pérez, Valentín CSIC ORCID ; Ferreras, Mª del Carmen CSIC ORCID | Palabras clave: | Tuberculosis Sheep Enteritis Granulomatous inflammation Mycobacterium avium subsp avium Intestinal adenocarcinoma |
Fecha de publicación: | 2013 | Editor: | Sage Publications | Citación: | Veterinary Pathology 50: 1158- 1162 (2013) | Resumen: | A 7-year-old dairy sheep suffering from chronic loss of weight without diarrhea or anorexia was euthanized after failing to respond to any treatment (antibiotic and antiparasitic). The main findings at the necropsy of this animal were multifocal miliary nodules in several organs, mainly in the Peyer's patches of the small intestine, and a segmental thickening of the jejunal wall. Histologic examination of the samples taken at the necropsy showed a multifocal chronic granulomatous inflammation, with mineralization and caseous necrosis at the core of the larger granulomas and scarce intrahistiocytic acid-fast bacilli consistent with a disseminated digestive tuberculosis. Polymerase chain reaction and bacteriological culture from these samples confirmed Mycobacterium avium subspavium to be the etiologic agent of this infection. Histologically, the cause of the segmental thickening of the jejunal wall was found to be a small intestine adenocarcinoma, which in some areas coexisted with the granulomatous lesion. © The Author(s) 2013. | Versión del editor: | http://dx.doi.org/10.1177/0300985813480214 | URI: | http://hdl.handle.net/10261/92371 | DOI: | 10.1177/0300985813480214 | ISSN: | 0300-9858 |
Aparece en las colecciones: | (IGM) Artículos |
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