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http://hdl.handle.net/10261/90637
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Chacón, F. | - |
dc.contributor.author | Cano Barquilla, Pilar | - |
dc.contributor.author | Jiménez, V. | - |
dc.contributor.author | Cardinal, D. P. | - |
dc.contributor.author | Marcos, Ascensión | - |
dc.contributor.author | Esquifino, Ana I. | - |
dc.date.accessioned | 2014-02-10T12:57:06Z | - |
dc.date.available | 2014-02-10T12:57:06Z | - |
dc.date.issued | 2004 | - |
dc.identifier | doi: 10.1081/CBI-120038607 | - |
dc.identifier | issn: 0742-0528 | - |
dc.identifier.citation | Chronobiology International 21: 393- 404 (2004) | - |
dc.identifier.uri | http://hdl.handle.net/10261/90637 | - |
dc.description.abstract | This work analyzes the effect of calorie restriction on the 24 h variation of pituitary-testicular function in young male Wistar rats by measuring the circulating levels of prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone. Control animals were provided an equilibrium calorie diet and the experimental animals a calorie-restriction diet equivalent to 66% of food restriction for four weeks starting on day 35 of life. Different groups of control and experimental rats were killed at 6 h intervals around the clock, beginning 1 h after light on (HALO). Compared to the control animals, the mean secretion of prolactin was augmented and that of LH and testosterone decreased in calorie-restricted rats, whereas FSH release remained unchanged. Significant changes in the 24 h secretory pattern of circulating prolactin, LH, and testosterone occurred in the calorie-restricted rats. These include the appearance of a second maximum of plasma prolactin at 21 HALO, blunting of the LH peak seen at 13 HALO, and phase-shift of the testosterone peak from 13 HALO in controls to 17 HALO in calorie-restricted rats. The significant positive correlation between individual LH and testosterone levels found in controls was no longer observed in calorie-restricted rats. Availability of nutrients presumably affects the mechanisms that modulate the circadian variation of the pituitary-gonadal axis in growing male rats. | - |
dc.language.iso | eng | - |
dc.publisher | Marcel Dekker | - |
dc.rights | closedAccess | - |
dc.title | 24-Hour changes in circulating prolactin, follicle-stimulating hormone, luteinizing hormone, and testosterone in young male rats subjected to calorie restriction | - |
dc.type | artículo | - |
dc.identifier.doi | 10.1081/CBI-120038607 | - |
dc.date.updated | 2014-02-10T12:57:06Z | - |
dc.description.version | Peer Reviewed | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.cerifentitytype | Publications | - |
item.openairetype | artículo | - |
item.languageiso639-1 | en | - |
item.grantfulltext | none | - |
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accesoRestringido.pdf | 15,38 kB | Adobe PDF | Visualizar/Abrir |
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