English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/90504
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:

Title

The genetic structure of Arabidopsis thaliana in the south-western Mediterranean range reveals a shared history between North Africa and southern Europe

AuthorsBrennan, Adrian C. ; Méndez-Vigo, Belén; Abdelmajid, Haddioui; Martínez-Zapater, José M. ; Picó, F. Xavier ; Alonso-Blanco, Carlos
KeywordsArabidopsis thaliana
Population genetics
Natural variation
Genetic diversity
Genetic structure
Demographic history
North Africa
Mediterraenan basin
Glacial refugium/refugia
Issue Date10-Jan-2014
PublisherBioMed Central
CitationBMC Plant Biology 14: 17 (2014)
Abstract[Background] Deciphering the genetic structure of Arabidopsis thaliana diversity across its geographic range provides the bases for elucidating the demographic history of this model plant. Despite the unique A. thaliana genomic resources currently available, its history in North Africa, the extreme southern limit in the biodiversity hotspot of the Mediterranean Basin, remains virtually unknown.
[Results] To approach A. thaliana evolutionary history in North Africa, we have analysed the genetic diversity and structure of 151 individuals collected from 20 populations distributed across Morocco. Genotyping of 249 genome-wide SNPs indicated that Morocco contains substantially lower diversity than most analyzed world regions. However, IBD, STRUCTURE and PCA clustering analyses showed that genetic variation is strongly geographically structured. We also determined the genetic relationships between Morocco and the closest European region, the Iberian Peninsula, by analyses of 201 populations from both regions genotyped with the same SNPs. These analyses detected four genetic groups, but all Moroccan accessions belonged to a common Iberian/Moroccan cluster that appeared highly differentiated from the remaining groups. Thus, we identified a genetic lineage with an isolated demographic history in the south-western Mediterranean region. The existence of this lineage was further supported by the study of several flowering genes and traits, which also found Moroccan accessions similar to the same Iberian group. Nevertheless, genetic diversity for neutral SNPs and flowering genes was higher in Moroccan than in Iberian populations of this lineage. Furthermore, we analyzed the genetic relationships between Morocco and other world regions by joint analyses of a worldwide collection of 337 accessions, which detected an additional weak relationship between North Africa and Asia.
[Conclusions] The patterns of genetic diversity and structure of A. thaliana in Morocco show that North Africa is part of the species native range and support the occurrence of a glacial refugium in the Atlas Mountains. In addition, the identification of a genetic lineage specific of Morocco and the Iberian Peninsula indicates that the Strait of Gibraltar has been an A. thaliana migration route between Europe and Africa. Finally, the genetic relationship between Morocco and Asia suggests another migration route connecting north-western Africa and Asia.
Publisher version (URL)http://dx.doi.org/10.1186/1471-2229-14-17
URIhttp://hdl.handle.net/10261/90504
DOIhttp://dx.doi.org/10.1186/1471-2229-14-17
ISSN1471-2229
Appears in Collections:(EBD) Artículos
(CNB) Artículos
(ICVV) Artículos
Files in This Item:
File Description SizeFormat 
1471-2229-14-17.pdf2,34 MBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.