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Title

In silico analysis of the regulatory region of the Yellowtail Kingfish and Zebrafish Kiss and Kiss receptor genes

AuthorsNocillado, J.N.; Mechaly, Alejandro S. ; Elizur, Abigail
KeywordsKisspeptin
Puberty
gpr54
Kiss
Issue DateFeb-2013
PublisherSpringer
CitationFish Physiology and Biochemistry 39(1): 59-63 (2013)
AbstractWe have cloned and analysed the partial putative promoter sequences of the Yellowtail Kingfish (Seriola lalandi) Kiss2 and Kiss2r genes (380 and 420 bp, respectively). We obtained in silico 1. 5 kb of the zebrafish (Danio rerio) Kiss1,Kiss2,Kiss1r and zfKiss2r sequences upstream of the putative transcriptional initiation site. Bioinformatic analysis revealed promoter regulatory elements including AP-1, Sp1, GR, ER, PR, AR, GATA-1, TTF-1, YY1 and C/EBP. These regulatory elements may mediate novel roles of the Kiss genes and their receptors in addition to their established role in reproductive function. © 2012 Springer Science+Business Media B.V.
Description5 pages, 2 figures
Publisher version (URL)http://dx.doi.org/10.1007/s10695-012-9642-0
URIhttp://hdl.handle.net/10261/89733
DOI10.1007/s10695-012-9642-0
Identifiersdoi: 10.1007/s10695-012-9642-0
issn: 0920-1742
e-issn: 1573-5168
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