English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/89207
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Citado 13 veces en Web of Knowledge®  |  Pub MebCentral Ver citas en PubMed Central  |  Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar otros formatos: Exportar EndNote (RIS)Exportar EndNote (RIS)Exportar EndNote (RIS)
Título

Organocatalyzed three-component Ugi and passerini reactions of 4-oxoazetidine-2-carbaldehydes and azetidine-2,3-diones. Application to the synthesis of γ-lactams and γ-lactones

Autor Alcaide, Benito ; Almendros, Pedro ; Aragoncillo, Cristina; Callejo, Ricardo; Ruiz, M. Pilar
Fecha de publicación 2013
EditorAmerican Chemical Society
Citación Journal of Organic Chemistry 78: 10154- 10165 (2013)
ResumenThe organocatalyzed U-3CR of 4-oxoazetidine-2-carbaldehydes has been studied. In addition, the organocatalyzed P-3CR of 4-oxoazetidine-2- carbaldehydes and azetidine-2,3-diones has been described for the first time. U-3CR and P-3CR adducts have been obtained in good yields and reasonable diastereoselectivities. Phenyl phosphinic acid has been the catalyst of choice to study the scope of both organocatalyzed multicomponent reactions using a variety of β-lactams, isocyanides, and amines. Highly functionalized U-3CR and P-3CR adducts derived from β-lactams have proved to be useful substrates for the preparation of enantiopure γ-lactams and γ-lactones via N1-C2 β-lactam ring opening/cyclization under acidic or basic conditions. © 2013 American Chemical Society.
URI http://hdl.handle.net/10261/89207
DOI10.1021/jo4015358
Identificadoresdoi: 10.1021/jo4015358
issn: 0022-3263
e-issn: 1520-6904
Aparece en las colecciones: (IQOG) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
485580.pdf395,13 kBUnknownVisualizar/Abrir
Mostrar el registro completo
 



NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.