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Doped TiO2 anodic layers of enhanced antibacterial properties

AuthorsArenas, M. A.; Pérez-Jorge, C.; Conde, A. ; Matykina, E.; Hernández-López, J. M.; Pérez-Tanoira, R.; Damborenea, Juan de ; Gómez-Barrena, E.; Esteba, J
KeywordsAntibacterial properties
Layer nanostructure
Ti-6Al-4V alloy
Issue Date2013
CitationColloids and Surfaces B: Biointerfaces 105: 106-112 (2013)
AbstractTi-6Al-4V joint replacement implants foster uncemented fixation in orthopaedic surgery. However, bacterial colonization competes with host cells and ultimately may produce implant-related difficult-to-treat infections, justifying the efforts to obtain infection-resistant materials. In a previous work, the authors demonstrated the antibacterial properties of anodic fluoride-TiO2 nanostructured layers on Ti-6Al-4V alloy. In this work, the anodizing bath has been modified in order to grow fluoride-TiO2 barrier layers (FBL). A bacterial adherence protocol, run with reference and six different clinical strains of Staphylococcus aureus and Staphylococcus epidermidis, showed a statistically significant decrease in the percentage of covered surface (p<0.0001, Kruskal-Wallis test) for FBL specimens when compared with non fluoride-containing specimens, i.e. chemically polished Ti-6Al-4V and F-free TiO2 barrier layers. The results obtained on the F-barrier layers allowed discrimination between the effects of the presence of fluoride in the layer and the layer nanostructure on bacterial adhesion. © 2013 Elsevier B.V.
Identifiersdoi: 10.1016/j.colsurfb.2012.12.051
issn: 0927-7765
Appears in Collections:(CENIM) Artículos
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