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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Thomson, Timothy M. | - |
dc.contributor.author | Guerra-Rebollo, Marta | - |
dc.date.accessioned | 2013-11-25T12:59:01Z | - |
dc.date.available | 2013-11-25T12:59:01Z | - |
dc.date.issued | 2010 | - |
dc.identifier | doi: 10.1042/BST0380116 | - |
dc.identifier | issn: 0300-5127 | - |
dc.identifier | e-issn: 1470-8752 | - |
dc.identifier.citation | Biochemical Society Transactions 38(1): 116-131 (2010) | - |
dc.identifier.uri | http://hdl.handle.net/10261/87485 | - |
dc.description.abstract | The repair of lesions and gaps in DNA follows different pathways, each mediated by specific proteins and complexes. Post-translational modifications in many of these proteins govern their activities and interactions, ultimately determining whether a particular pathway is followed. Prominent among these modifications are the addition of phosphate or ubiquitin (and ubiquitin-like) moieties that confer new binding surfaces and conformational states on the modified proteins. The present review summarizes some of consequences of ubiquitin and ubiquitin-like modifications and interactions that regulate nucleotide excision repair, translesion synthesis, double-strand break repair and interstrand cross-link repair, with the discussion of relevant examples in each pathway. © The Authors Journal compilation. | - |
dc.description.sponsorship | M.G-R. is funded by a fellowship of the Spanish Ministry of Science. This work was supported by Spanish Ministry of Science [grant number SAF2008-04136-C02-01] and institutional funds provided by the Centre de Referència en Biotecnologia (Generalitat de Catalunya). | - |
dc.language.iso | eng | - |
dc.publisher | Biochemical Society | - |
dc.rights | closedAccess | - |
dc.title | Ubiquitin and SUMO signalling in DNA repair | - |
dc.type | artículo | - |
dc.identifier.doi | 10.1042/BST0380116 | - |
dc.date.updated | 2013-11-25T12:59:01Z | - |
dc.description.version | Peer Reviewed | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
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