English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/8683
COMPARTIR / IMPACTO:
Estadísticas
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Título

SPACE: an algorithm to predict and quantify alternatively spliced isoforms using microarrays

AutorAntón, Miguel A.; Gorostiaga, Dorleta; Guruceaga, Elizabeth; Segura, Víctor; Carmona-Sáez, Pedro; Pascual-Montano, Alberto; Pio, Rubén; Montuenga, Luis M.; Rubio, Angel
Palabras claveBioinformatics
Molecular biology
Genome studies
Fecha de publicación29-feb-2008
EditorBioMed Central
CitaciónGenome Biol. 9(2):R46 (2008)
ResumenExon and exon+junction microarrays are promising tools for studying alternative splicing. Current analytical tools applied to these arrays lack two relevant features: the ability to predict unknown spliced forms and the ability to quantify the concentration of known and unknown isoforms. SPACE is an algorithm that has been developed to (1) estimate the number of different transcripts expressed under several conditions, (2) predict the precursor mRNA splicing structure and (3) quantify the transcript concentrations including unknown forms. The results presented here show its robustness and accuracy for real and simulated data.
Descripción20 pages, 13 figures.-- Supplementary material available at: http://genomebiology.com/2008/9/2/R46/additional/ (Additional data file 1: 22 Figures. Additional data file 2: Matlab data files).-- PMCID: PMC2374713.
Versión del editorhttp://dx.doi.org/10.1186/gb-2008-9-2-r46
URIhttp://hdl.handle.net/10261/8683
DOI10.1186/gb-2008-9-2-r46
ISSN1465-6906 (Print)
1465-6914 (Online)
Aparece en las colecciones: (CNB) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
SPACE.pdfArticle Final Version799,95 kBAdobe PDFVista previa
Visualizar/Abrir
Additional_file_1.pdfAdditional file 1299,02 kBAdobe PDFVista previa
Visualizar/Abrir
Additional_file_2.zipAdditional file 221,56 kBUnknownVisualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.