Changes in crystalline lens radii of curvature and lens tilt and decentration during dynamic accommodation in rhesus monkeys

Abstract

Dynamic changes in crystalline lens radii of curvature and lens tilt and decentration were measured during centrally stimulated accommodation in four iridectomized eyes of two adolescent rhesus monkeys. Phakometry measurements were performed dynamically using a custom-built, video-based, Purkinje-image instrument. Lens anterior and posterior radii were calculated from reflections of paired light sources from the ocular surfaces (Purkinje images PI, PIII, and PIV). Lens tilt and decentration were calculated assuming linearity between Purkinje image positions, eye rotation, lens tilt, and decentration. Because the monkey eyes were iridectomized, Purkinje images were referred to the mid-point of the double first Purkinje image (PI). Mean unaccommodated values of anterior and posterior lens radii of curvature were 11.11 ± 1.58 mm and −6.64 ± 0.62 mm, respectively, and these decreased relatively linearly with accommodation in all eyes, at a rate of 0.48 ± 0.14 mm/D and 0.17 ± 0.03 mm/D for anterior and posterior lens surfaces, respectively. Tilt and decentration did not change significantly with accommodation except for tilt around the horizontal axis, which changed at a rate of 0.147 ± 0.25 deg/D. These results are important to fully characterize accommodation in rhesus monkeys.