English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/84016
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Immunotherapy for neurological diseases

AuthorsVilloslada, Pablo; Moreno, Beatriz; Melero, Ignacio; Pablos, José Luis; Martino, Gianvito; Uccelli, Antonio; Montalbán, X.; Ávila, Jesús ; Rivest, Serge; Acarin, Laia; Appel, Stanley; Khoury, Sarnia J.; McGeer, Patrick; Ferrer, Isidro; Delgado, M.; Obeso, José Ángel; Schwartz, Michal
Issue Date2008
PublisherAcademic Press
CitationClinical Immunology 128: 294- 305 (2008)
AbstractThe burden of neurological diseases in western societies has accentuated the need to develop effective therapies to stop the progression of chronic neurological diseases. Recent discoveries regarding the role of the immune system in brain damage coupled with the development of new technologies to manipulate the immune response make immunotherapies an attractive possibility to treat neurological diseases. The wide repertoire of immune responses and the possibility to engineer such responses, as well as their capacity to promote tissue repair, indicates that immunotherapy might offer benefits in the treatment of neurological diseases, similar to the benefits that are being associated with the treatment of cancer and autoimmune diseases. However, before applying such strategies to patients it is necessary to better understand the pathologies to be targeted, as well as how individual subjects may respond to immunotherapies, either in isolation or in combination. Due to the powerful effects of the immune system, one priority is to avoid tissue damage due to the activity of the immune system, particularly considering that the nervous system does not tolerate even the smallest amount of tissue damage. © 2008 Elsevier Inc. All rights reserved.
URIhttp://hdl.handle.net/10261/84016
DOI10.1016/j.clim.2008.04.003
Identifiersdoi: 10.1016/j.clim.2008.04.003
issn: 1521-6616
Appears in Collections:(CBM) Artículos
(IPBLN) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.