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Title

Static and dynamic crystalline lens accommodation evaluated using quantitative 3-D OCT

AuthorsGambra, Enrique ; Ortiz, Sergio ; Pérez Merino, Pablo ; Gora, Michalina; Wojtkowski, Maciej; Marcos, Susana
Issue Date2013
PublisherOptical Society of America
CitationBiomedical Optics Express 4(9): 1595-1609 (2013)
AbstractCustom high-resolution high-speed anterior segment spectral domain Optical Coherence Tomography (OCT) provided with automatic quantification and distortion correction algorithms was used to characterize three-dimensionally (3-D) the human crystalline lens in vivo in four subjects, for accommodative demands between 0 to 6 D in 1 D steps. Anterior and posterior lens radii of curvature decreased with accommodative demand at rates of 0.73 and 0.20 mm/D, resulting in an increase of the estimated optical power of the eye of 0.62 D per diopter of accommodative demand. Dynamic fluctuations in crystalline lens radii of curvature, anterior chamber depth and lens thickness were also estimated from dynamic 2-D OCT images (14 Hz), acquired during 5-s of steady fixation, for different accommodative demands. Estimates of the eye power from dynamical geometrical measurements revealed an increase of the fluctuations of the accommodative response from 0.07 D to 0.47 D between 0 and 6 D (0.044 D per D of accommodative demand). A sensitivity analysis showed that the fluctuations of accommodation were driven by dynamic changes in the lens surfaces, particularly in the posterior lens surface. © 2013 Optical Society of America.
URIhttp://hdl.handle.net/10261/84004
DOI10.1364/BOE.4.001595
Identifiersdoi: 10.1364/BOE.4.001595
issn: 2156-7085
Appears in Collections:(CFMAC-IO) Artículos
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