Heterocyclic inhibitors of glycogen synthase kinase GSK-3

Abstract

Compounds of formula (II) where Ra, Rb, Y and X take various meanings are of use in the preparation of a pharmaceutical formulation, for example in the treatment of a disease in which GSK-3 is involved, including Alzheimer's disease or the non-dependent insulin diabetes mellitus, or hyperproliferative disease such as cancer, displasias or metaplasias of tissue, psoriasis, arterosclerosis or restenosis