Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/79042
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Prolactin receptor is associated with c-src kinase in rat liver |
Autor: | Berlanga, Juan José; Fresno Vara, Juan Ángel CSIC; Martín-Pérez, Jorge CSIC ORCID ; García-Ruiz, Josefa P. | Fecha de publicación: | 1995 | Editor: | Endocrine Society | Citación: | Molecular Endocrinology 9(11): 1461-1467 (1995) | Resumen: | The mechanism of action of the pituitary hormone PRL was studied in hepatocytes of lactating rats. PRL receptor immune complexes obtained from liver lysates have an associated tyrosine kinase activity. The tyrosine kinase has been identified in isolated hepatocytes as pp60c-src. Incubation of hepatocytes with PRL induces the association of PRL receptor with pp60c-src and the resultant stimulation of its tyrosine kinase activity. Furthermore, PRL stimulates the gene expression of c-fos, c-jun, and c-src. All of these findings support the idea that the pp60c-src tyrosine kinase participates in the early steps of the PRL intracellular signaling that promotes cell growth in liver cells. | Versión del editor: | http://dx.doi.org/10.1210/me.9.11.1461 | URI: | http://hdl.handle.net/10261/79042 | DOI: | 10.1210/me.9.11.1461 | Identificadores: | doi: 10.1210/me.9.11.1461 issn: 0888-8809 e-issn: 1944-9917 |
Aparece en las colecciones: | (IIBM) Artículos (CBM) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
387030.null | 1,52 MB | Unknown | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
83
checked on 21-abr-2024
WEB OF SCIENCETM
Citations
84
checked on 26-feb-2024
Page view(s)
390
checked on 24-abr-2024
Download(s)
371
checked on 24-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.