English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/77784
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Title

Psychomotor development of children from an iodine-deficient region

AuthorsCosteira, Maria José; Oliveira, Pedro; Correia Santos, Nadine; Ares, Susana; Morreale de Escobar, Gabriella ; Almeida Palha, Joana
Issue Date2011
PublisherElsevier
CitationJournal of Pediatrics 159(3): 447-453 (2011)
Abstract[Objectives]: To assess the psychomotor development of the progeny of women from a moderately iodine-deficient area for whom thyroid function during pregnancy was measured. [Study design]: The development of 86 children was assessed by the Bayley Scale of Infant Development at 12, 18, and 24 months. [Results]: Maternal serum free thyroxine (FT4) levels in the first trimester of pregnancy were the major determinant of psychomotor development at 18 and 24 months. Children born from mothers with FT4 levels <25th percentile (<10 pg/mL) had an OR of 2.1 for mild-to-severe delay. Furthermore, alterations in behavior were already observed at 12 months and were related to subsequent changes in development. Neonatal thyroid status did not influence development. [Conclusions]: This study highlights the need to implement active measures of iodine supplementation periconceptionally and during pregnancy and lactation because the negative effects on development and behavior might be prevented through preemptive action. © 2011 Mosby Inc. All rights reserved.
URIhttp://hdl.handle.net/10261/77784
DOI10.1016/j.jpeds.2011.02.034
Identifiersdoi: 10.1016/j.jpeds.2011.02.034
issn: 0022-3476
e-issn: 1097-6833
Appears in Collections:(IIBM) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.