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http://hdl.handle.net/10261/73975
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Lomba, Miguel | - |
dc.contributor.author | Oriol, Luis | - |
dc.contributor.author | Sánchez-Somolinos, Carlos | - |
dc.contributor.author | Grazú, Valeria | - |
dc.contributor.author | Sáez Gutiérrez, Berta | - |
dc.contributor.author | Serrano, José Luis | - |
dc.contributor.author | Fuente, Jesús M. de la | - |
dc.date.accessioned | 2013-04-10T08:31:30Z | - |
dc.date.available | 2013-04-10T08:31:30Z | - |
dc.date.issued | 2012 | - |
dc.identifier | doi: 10.1016/j.carbpol.2012.05.061 | - |
dc.identifier | issn: 0144-8617 | - |
dc.identifier.citation | Carbohydrate Polymers 90(1): 419-430 (2012) | - |
dc.identifier.uri | http://hdl.handle.net/10261/73975 | - |
dc.description.abstract | Chemically unmodified sodium hyaluronate has been crosslinked by photoinduced decomposition of a trifunctional diazonium salt to generate new biomaterials. In addition, the photocrosslinking process does not require a photoinitiator. Thin films of formulations of sodium hyaluronate and the photocrosslinker at different percentages have been processed. Cytotoxicity has been explored and toxicity was not observed with the selected cell lines. 2D patterns of controlled geometry have been generated by direct laser writing to perform cell adhesion studies. Different adhesion behavior of the cell lines, as assessed by vinculin immunostaining and scanning electron microscopy, has been observed in the polymeric films depending on the degree of photocrosslinking. © 2012 Elsevier Ltd. | - |
dc.description.sponsorship | This work was supported by the Spanish MEC project MAT2011-27978-C02 and MAT2011-26851-C02-01, ARAID project for young scientists, ERC-Starting Grant NANOPUZZLE and FEDER funding (EU). M. Lomba thanks the Gobierno de Aragón (Spain) for a PhD. Grant. JM de la Fuente thanks ARAID for financial support. B. Saez Gutiérrez thanks ISCIII for financial support (Sara Borrell CD09/00174). | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier | - |
dc.rights | closedAccess | - |
dc.title | Photocrosslinking, micropatterning and cell adhesion studies of sodium hyaluronate with a trisdiazonium salt | - |
dc.type | artículo | - |
dc.identifier.doi | 10.1016/j.carbpol.2012.05.061 | - |
dc.date.updated | 2013-04-10T08:31:31Z | - |
dc.description.version | Peer Reviewed | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | artículo | - |
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