English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/73489
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

DC FieldValueLanguage
dc.contributor.authorLi, C.-
dc.contributor.authorAldai, Noelia-
dc.contributor.authorVinsky, M.-
dc.contributor.authorDugan, M. E. R.-
dc.contributor.authorMcAllister, T. A.-
dc.identifier.citationAnimal Genetics: Immunogenetics, Molecular Genetics and Functional Genomics 43(1) : 93-97 (2012)es_ES
dc.description5 páginas, 3 tablas.es_ES
dc.description.abstractTwo previously reported non-synonymous coding single nucleotide polymorphisms (SNPs) of bovine stearoyl-CoA desaturase (delta-9-desaturase) (SCD) (c.878C>T) and fatty acid synthase (FASN) (g:17924A>G) were assessed for their associations with 72 individual and 12 groups of fatty acids in brisket adipose tissue of 223 Canadian commercial cross-bred beef steers. It was found that the ‘CC’ genotype of the SCD SNP was significantly associated with lower concentrations of saturated fatty acids (SFA) including 10:0, 14:0 and 20:0, higher concentrations of monounsaturated fatty acids including 9c-14:1, 12c-16:1 and 13c-18:1, higher concentrations of polyunsaturated fatty acids (PUFA) including 9c,15c-18:2, 10c,12c-18:2, 11c,13t-18:2 and 12c,14t-18:2, but lower concentrations of other PUFA of 9c,13t/8t,12c and 20:2n-6 (P < 0.05). The ‘AA’ genotype of the FASN SNP was significantly associated with higher concentrations of SFAs of 10:0, 12:0, 13:0, 14:0 and 15:0, lower concentrations of unsaturated fatty acids of 9c-18:1 and 20:3n-6, and higher concentrations of unsaturated fatty acids of 9c-14:1 and 12c-16:1 (P < 0.05). Significant epistatic effects between the SCD and FASN SNP genotypes were also found for several fatty acids including 10:0, 23:0, 6t/7t/8t-18:1, 12t-18:1, 13t/14t-18:1, 16t-18:1, total trans18:1 and 9c,13t/8t,12c-18:2 (P < 0.05). These results further suggest that SCD and FASN are strong candidate genes influencing fatty acid composition in beef cattle.es_ES
dc.description.sponsorshipAAFC Matching Investment Initiative (MII). Alberta Livestock and Meat Agency (ALMA) 2010R038R. European Community PIOF-GA-2008-220730es_ES
dc.subjectFatty acid composition in beef cattlees_ES
dc.subjectFatty acid synthasees_ES
dc.subjectSingle nuceotide polymorphismes_ES
dc.subjectStearoyl-CoA desaturasees_ES
dc.titleAssociation analyses of single nucleotide polymorphisms in bovine stearoyl-CoA desaturase and fatty acid synthase genes with fatty acid composition in commercial cross-bred beef steerses_ES
dc.description.peerreviewedPeer reviewedes_ES
Appears in Collections:(IGM) Artículos
Files in This Item:
File Description SizeFormat 
Embargo. Digital.CSIC..pdf21,67 kBAdobe PDFThumbnail
Show simple item record

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.