1. DIGITAL.CSIC
  2. Biología y Biomedicina
  3. Instituto de Biología y Genética Molecular (IBGM)
  4. (IBGM) Artículos
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/71668
COMPARTIR / EXPORTAR:
logo share SHARE logo core CORE BASE

Comparte tu historia
de Acceso Abierto
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE

Invitar a revisión por pares abierta
Campo DC Valor Lengua/Idioma
dc.contributor.authorLioubinski, Oleg-
dc.contributor.authorAlonso, María Teresa-
dc.contributor.authorAlvarez, Yolanda-
dc.contributor.authorVendrell, Victor-
dc.contributor.authorSchimmang, Thomas-
dc.date.accessioned2013-03-07T10:30:14Z-
dc.date.available2013-03-07T10:30:14Z-
dc.date.issued2006-
dc.identifierdoi: 10.1016/j.mod.2005.10.004-
dc.identifierissn: 0925-4773-
dc.identifier.citationMechanisms of Development 123(1): 17-23 (2006)-
dc.identifier.urihttp://hdl.handle.net/10261/71668-
dc.descriptionEl pdf del artículo es la versión pre-print.-- et al.-
dc.description.abstractFibroblast growth factors (FGFs) have been shown to control formation and differentiation of multiple organ systems in the developing vertebrate embryo. The analysis of differential gene expression during embryogenesis is, therefore, a potent tool to identify novel target genes regulated by FGF signalling. Here, we have applied microarray analysis to identify differentially regulated genes in FGF mutant mouse embryos. Surprisingly, transcripts corresponding to vomeronasal receptors (VRs), which so far have been only detected in the vomeronasal organ (VNO), were found to be downregulated in FGF mutant embryos. VR expression was detected in the developing olfactory pit and the anlage of the VNO. Interestingly, several FGFs can be detected in the developing olfactory pit during mouse embryogenesis [Bachler, M., Neubuser, A. 2001. Expression of members of the Fgf family and their receptors during midfacial development. Mech. Dev. 100, 313-316]. FGF signalling may thus control expression of VRs in the olfactory pit and formation of the VNO. Moreover, VR expression was detected in unexpected locations within the developing embryo including retina, dorsal root ganglia and neural tube. The relevance of VR expression in these structures and for formation of the VNO is discussed. © 2005 Elsevier Ireland Ltd. All rights reserved.-
dc.description.sponsorshipThis work has been generously supported by Deutsche Forschungsgemeinschaft (SFB444) and grant BFU2004-00860 of the Spanish MEC.-
dc.language.isoeng-
dc.publisherElsevier-
dc.rightsopenAccess-
dc.titleFGF signalling controls expression of vomeronasal receptors during embryogenesis-
dc.typeartículo-
dc.identifier.doi10.1016/j.mod.2005.10.004-
dc.relation.publisherversionhttp://dx.doi.org/10.1016/j.mod.2005.10.004-
dc.date.updated2013-03-07T10:30:14Z-
dc.description.versionPeer Reviewed-
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.languageiso639-1en-
item.fulltextWith Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.grantfulltextopen-
item.openairetypeartículo-
Aparece en las colecciones: (IBGM) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato
FGF signalling.pdf916,75 kBAdobe PDFVista previa
Visualizar/Abrir
Show simple item record

CORE Recommender

SCOPUSTM   
Citations

8
checked on 21-abr-2024

WEB OF SCIENCETM
Citations

7
checked on 28-feb-2024

Page view(s)

337
checked on 24-abr-2024

Download(s)

420
checked on 24-abr-2024

Google ScholarTM

Check

Altmetric

Altmetric


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.