Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/69312COMPARTIR / EXPORTAR:
 SHARE
 CORE
BASE
|
|
| Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.contributor.author | Briales, Alejandra | - |
| dc.contributor.author | Rodríguez-Martínez, José-Manuel | - |
| dc.contributor.author | Velasco, Carmen | - |
| dc.contributor.author | Díaz-de-Alba, Paula | - |
| dc.contributor.author | Domínguez-Herrera, Juan | - |
| dc.contributor.author | Pachón, Jerónimo | - |
| dc.contributor.author | Pascual, Álvaro | - |
| dc.date.accessioned | 2013-02-28T13:25:28Z | - |
| dc.date.available | 2013-02-28T13:25:28Z | - |
| dc.date.issued | 2011 | - |
| dc.identifier | doi: 10.1128/AAC.00927-10 | - |
| dc.identifier | issn: 0066-4804 | - |
| dc.identifier.citation | Antimicrobial Agents and Chemotherapy 55(3): 1266-1269 (2011) | - |
| dc.identifier.uri | http://hdl.handle.net/10261/69312 | - |
| dc.description.abstract | This article provides an analysis of the in vitro effect of qnrA1, qnrB1, and qnrS1 genes, combined with quinolone-resistant Ser83Leu substitutions in GyrA and/or Ser80Arg in ParC, on fluoroquinolone (FQ) resistance in isogenic Escherichia coli strains. The association of Ser83Leu substitution in GyrA, Ser80Arg substitution in ParC, and qnr gene expression increased the MIC of ciprofloxacin to 2 μg/ml. qnr genes present in E. coli that harbored a Ser83Leu substitution in GyrA increased mutant prevention concentration (MPC) values to 8 to 32 μg/ml. qnr gene expression in E. coli may play an important role in selecting for one-step FQ-resistant mutants. Copyright © 2011, American Society for Microbiology. All Rights Reserved. | - |
| dc.description.sponsorship | This work was supported by the Ministerio de Sanidad y Consumo, Instituto de Salud Carlos III (project PI060580) and the Consejería de Innovacio´n Ciencia y Empresa, Junta de Andalucía (P07-CTS-02908), Spain. It was partly supported by the Ministerio de Sanidad y Consumo, Instituto de Salud Carlos III-FEDER, Spanish Network for Research in Infectious Diseases (REIPI RD06/0008). A.B. was funded by a predoctoral grant from the Instituto de Salud Carlos III (PFIS), Spain. | - |
| dc.language.iso | eng | - |
| dc.publisher | American Society for Microbiology | - |
| dc.rights | closedAccess | - |
| dc.title | In vitro effect of qnrA1, qnrB1, and qnrS1 genes on fluoroquinolone activity against isogenic Escherichia coli isolates with mutations in gyrA and parC | - |
| dc.type | artículo | - |
| dc.identifier.doi | 10.1128/AAC.00927-10 | - |
| dc.date.updated | 2013-02-28T13:25:28Z | - |
| dc.description.version | Peer Reviewed | - |
| dc.identifier.pmid | 21173174 | - |
| dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
| item.openairetype | artículo | - |
| item.grantfulltext | none | - |
| item.cerifentitytype | Publications | - |
| item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
| item.fulltext | No Fulltext | - |
| item.languageiso639-1 | en | - |
| Aparece en las colecciones: | (IBIS) Artículos | |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| accesoRestringido.pdf | 15,38 kB | Adobe PDF |  Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
21
checked on 19-abr-2024
SCOPUSTM
Citations
49
checked on 12-abr-2024
WEB OF SCIENCETM
Citations
46
checked on 27-feb-2024
Page view(s)
344
checked on 18-abr-2024
Download(s)
117
checked on 18-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
Artículos relacionados:
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.