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Título

Ubiquity and diversity of multidrug resistance genes in Lactococcus lactis strains isolated between 1936 and 1995

Autor Flórez García, Ana Belén ; González de los Reyes-Gavilán, Clara ; Wind, Anette; Mayo Pérez, Baltasar ; Margolles Barros, Abelardo
Palabras clave Lactococcus lactis
Multidrug resistance
MDR-transporters
Fecha de publicación 21-ago-2006
EditorFederation of European Microbiological Societies
Citación FEMS Microbiology Letters 263(1): 21-25 (2006)
ResumenThe presence and the nucleotide sequence of four multidrug resistance genes, lmrA, lmrP, lmrC, and lmrD, were investigated in 13 strains of Lactococcus lactis ssp. lactis, four strains of Lactococcus lactis ssp. cremoris, two strains of Lactococcus plantarum, and two strains of Lactococcus raffinolactis. Multidrug resistance genes were present in all L. lactis isolates tested. However, none of them could be detected in the strains belonging to the species L. raffinolactis and L. plantarum, suggesting a different set of multidrug resistance genes in these species. The analysis of the four deduced amino acid sequences established two different variants depending on the subspecies of L. lactis. Either lmrA, or lmrP, or both were found naturally disrupted in five strains, while full-length lmrD was present in all strains
URI http://hdl.handle.net/10261/6804
DOI10.1111/j.1574-6968.2006.00371.x
ISSN0378-1097
E-ISSN1574-6968
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